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Thiamin-responsive maple syrup urine disease: seizures after 7 years of satisfactory metabolic control.
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The thiamin deficiency signs and requirement of rainbow trout (Salmo gairdneri, Richardson).
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Four growth studies were conducted to determine the signs, biochemical indices and histopathology of a thiamin deficiency and the thiamin requirement of young rainbow trout reared at 15°C on a semi-purified test diet. The major overt signs of a thiamin deficiency in rainbow trout are predominantly
Effect of a single, large dose injection of pyrithiamin on the thiamin deficiency of the mouse.
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The effect of pyrithiamin on thiamin deficient mice was studied clinically and pathologically. Thiamin deficiency was produced in the mice fed with a thiamin deficient diet by a single injection of pyrithiamin (10 mg/kg, s.c.) on day 0 to produce a mild illness and on day 14 to produce a severe
Effect of high-dose vitamins, coenzyme Q and high-fat diet in paediatric patients with mitochondrial diseases.
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We reviewed the medical records of all patients with confirmed mitochondrial diseases treated with any or all of thiamin, riboflavin, coenzyme Q, vitamin C (approximately 10 mg/kg per day) and a high-fat diet (50-60% of caloric intake) between 1997 and 2003. There were 15 patients (9 male): 10 had
[Alcohol dependence: diagnosis and treatment].
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OBJECTIVE
Prevalence of alcohol dependence remains stable across time between 5-7% in men and 2-3% in women, corresponding to at least 1.5 million patients in France. A review about alcohol dependence is warranted, not only as prevalence of this disease is high, but also because of recent
[Marchiafava-Bignami disease (Case-report)].
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Marchiafava-Bignami disease (MBD) is caused by damage of the corpus callosum. There are acute, subacute and chronic forms, it occurs most frequently among alcoholic patients. A variety of neurological symptoms, epileptic seizures, and coma may be associated with the disease, but the chronic form may
Single gene, two diseases, and multiple clinical presentations: Biotin-thiamine-responsive basal ganglia disease
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Aim: To present seven new genetically confirmed cases of biotin-thiamin-responsive basal ganglia disease (BTBGD) with different clinical and brain magnetic resonance imaging (MRI) characteristics.
Amitriptyline and tianeptine poisoning treated by naloxone.
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BACKGROUND
Severe amitriptyline toxicity may cause cardiac dysrhythmias, severe hypotension, convulsions and CNS depression, including coma. Management with gastric lavage, activated charcoal, alkalinization and supportive care with mechanical ventilation, antiarrhythmics and anticonvulsants, if
A history of the isolation and identification of vitamin B(6).
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In the 1930s, Rudolf Peters showed that young rats kept on a semi-synthetic diet with added thiamin and riboflavin but no other supplement developed 'rat acrodynia', a condition characterized by severe cutaneous lesions. In 1934, Paul György showed that the factor which cured 'rat acrodynia' was
Neurologic conditions and disorders of uremic syndrome of chronic kidney disease: presentations, causes, and treatment strategies.
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Introduction: Uremic syndrome of chronic kidney disease (CKD) is a term used to describe clinical, metabolic, and hormonal abnormalities associated with progressive kidney failure. It is a rapidly growing public health problem worldwide. Nervous system complications occur in every patient
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