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trans communic acid/dacrydium cupressinum

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The natural phytochemical trans-communic acid inhibits cellular senescence and pigmentation through FoxO3a activation.

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Aging is characterized by the accumulation of chronic and irreversible oxidative damage, chronic inflammation, and organ dysfunction. To attenuate these aging-related changes, various natural phytochemicals are often applied. Trans-communic acid (TCA), an active component of brown pine leaf extract,

Brown Pine Leaf Extract and Its Active Component Trans-Communic Acid Inhibit UVB-Induced MMP-1 Expression by Targeting PI3K.

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Japanese red pine (Pinus densiflora) is widely present in China, Japan, and Korea. Its green pine leaves have traditionally been used as a food as well as a coloring agent. After being shed, pine leaves change their color from green to brown within two years, and although the brown pine leaves are
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