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The reversal of cisplatin-induced nephrotoxicity by selenium nanoparticles functionalized with 11-mercapto-1-undecanol by inhibition of ROS-mediated apoptosis.
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Although cisplatin is still one of the most effective chemotherapy agents for human cancers, its clinical use is limited by serious side effects, especially nephrotoxicity. Oxidative stress is an important mediator of cisplatin-induced nephrotoxicity. In the present study, a simple method for
Inhibitory effect of the alkyl side chain of caffeic acid analogues on lipopolysaccharide-induced nitric oxide production in RAW264.7 macrophages.
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Caffeic acid esters, one of the components of propolis, are known to show a variety of biological effects such as anti-tumor, anti-oxidant, and anti-inflammatory activities. Although, the anti-inflammatory activities of caffeic acid esters have been studied by analyzing their structure, the detailed
Release of Cyt c from the model membrane due to conformational change induced by anticancer palladium complex.
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Cytochrome C (Cyt c) is an electron transporting protein that resides within the inter-membrane space of the mitochondria. It plays a critical role as an electron carrier in the process of oxidative phosphorylation and production of cellular ATP. Cyt c is also involved in the apoptosis process and
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