vincamine/catharanthus

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Vincamine as a GPR40 agonist improves glucose homeostasis in type 2 diabetic mice.

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Vincamine, a monoterpenoid indole alkaloid extracted from madagascar periwinkle, is clinically used for the treatment of cardio-cerebrovascular diseases, while also treated as a dietary supplement with nootropic function. Given the neuronal protection of vincamine and the potency of β-cell

The ATP binding cassette transporter, VmTPT2/VmABCG1, is involved in export of the monoterpenoid indole alkaloid, vincamine in Vinca minor leaves.

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Vinca minor is a herbaceous plant from the Apocynaceae family known to produce over 50 monoterpene indole alkaloids (MIAs). These include several biologically active MIAs that have a range of pharmaceutical activities. The present study shows that the MIAs, vincamine, akuammicine, minovincinine,

[Various physiological properties of vincamine, a crystallized alkaloid of lesser periwinkle (Vinca minor L.)].

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Phytochemical Investigation of Vinca minor Cultivated in Iran.

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Lesser Periwinkle (Vinca minor L.), a member of Apocynaceae, is not only an ornamental plant with lilac-blue flowers, but also a medical plant producing an important alkaloid, vincamine, found in the leaves which shows a pronounced cerebrovasodilatory and neuroprotective activity. This plant is

Over-expression of Catharanthus roseus tryptophan decarboxylase and strictosidine synthase in rol gene integrated transgenic cell suspensions of Vinca minor.

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Tryptophan decarboxylase (TDC) and strictosidine synthase (STR) genes from Catharanthus roseus have been successfully over-expressed in the rol gene integrated cell suspensions of V. minor. Thirty seconds SAAT (sonication-assisted Agrobacterium transformation) treatment of plant cell suspension with

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