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Association between higher plasma lutein, zeaxanthin, and vitamin C concentrations and longer telomere length: results of the Austrian Stroke Prevention Study.

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OBJECTIVE To examine the association between plasma concentrations of antioxidative micronutrients and leukocyte telomere length (LTL) in elderly adults. METHODS Cross-sectional cohort study. METHODS Austrian Stroke Prevention Study, a population-based cohort study on brain

Intake of flavonoids, carotenoids, vitamins C and E, and risk of stroke in male smokers.

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OBJECTIVE Antioxidants may protect against atherosclerosis and thus prevent cerebrovascular disease. We studied the association between dietary antioxidants and subtypes of stroke. METHODS The study cohort consisted of 26 593 male smokers, aged 50 to 69 years, without a history of stroke. They were

Carotenoids as Potential Antioxidant Agents in Stroke Prevention: A Systematic Review.

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Stroke and other cerebrovascular diseases are among the most common causes of death worldwide. Prevention of modifiable risk factors is a cost-effective approach to decrease the risk of stroke. Oxidative stress is regarded as the major flexible operative agent in ischemic brain damage. This review

Lutein and zeaxanthin and their potential roles in disease prevention.

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Lutein and zeaxanthin are xanthophyll carotenoids found particularly in dark-green leafy vegetables and in egg yolks. They are widely distributed in tissues and are the principal carotenoids in the eye lens and macular region of the retina. Epidemiologic studies indicating an inverse relationship

Plasma carotenoid and malondialdehyde levels in ischemic stroke patients: relationship to early outcome.

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An association between ischemic stroke and increased oxidative stress has been suggested from animal studies. However, there is a lack of evidence with respect to this association in humans. Here, the time course of plasma levels of six carotenoids, which are lipophilic micronutrients with

Effect of long-chain ω-3 fatty acids and lutein + zeaxanthin supplements on cardiovascular outcomes: results of the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial.

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OBJECTIVE Dietary supplements have been proposed as a mechanism to improve health and prevent disease. OBJECTIVE To determine if supplementing diet with long-chain ω-3 polyunsaturated fatty acids or with macular xanthophylls results in a reduced rate of cardiovascular disease (CVD). METHODS The

Plasma antioxidants and cognitive performance in middle-aged and older adults: results of the Austrian Stroke Prevention Study.

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OBJECTIVE To study the association between cognitive status and plasma concentrations of various antioxidants in middle-aged and older individuals without neuropsychiatric disease. METHODS Evaluation of cross-sectional data from a cohort study. METHODS The Austrian Stroke Prevention Study. METHODS A

Plasma lycopene, other carotenoids, and retinol and the risk of cardiovascular disease in men.

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BACKGROUND Emerging evidence suggests a possible role of lycopene in the primary prevention of cardiovascular disease (CVD). OBJECTIVE We examined whether plasma lycopene concentrations in the Physicians' Health Study were associated with CVD in a prospective, nested, case-control

Dietary antioxidant intake is associated with the prevalence but not incidence of age-related hearing loss.

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OBJECTIVE Diet is one of the few modifiable risk factors for age-related hearing loss. We aimed to examine the link between dietary and supplement intakes of antioxidants, and both the prevalence and 5-year incidence of measured hearing loss. METHODS Cross-sectional and 5-year longitudinal

Carotenoids and cardiovascular risk.

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Fruits and vegetables (typically associated with the Mediterranean diet) are very rich in carotenoids, i.e. fat-soluble pigments really important in human life. Structurally, carotenoids consists of eleven (beta-carotene, zeaxanthin, lycopene) or ten (alpha-carotene, lutein) conjugated double bonds,

Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration.

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There is inconclusive evidence from observational studies to suggest that people who eat a diet rich in antioxidant vitamins (carotenoids, vitamins C, and E) or minerals (selenium and zinc) may be less likely to develop age-related macular degeneration (AMD). To determine whether or not taking

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