IDH in Diabetic Haemodialysis Patients and Association With Dialytic Age
Paraules clau
Resum
Descripció
Intradialytic hypotension (IDH ) is a serious and the most frequent complication of hemodialysis of the hemodialysis.Intradialytic hypotension is a decrease in systolic BP by ≥20 mm Hg or a decrease in mean arterial pressure of 10 mm Hg associated with symptoms like cramps, dizziness, headache ,nausea and vomiting according to The National Kidney Foundation.Intradialytic hypotension occurs during 20%-30% of hemodialysis sessions. It is associated with poor long-term outcomes. Patients with Intradialytic hypotension show increased morbidity and mortality.The etiology of Intradialytic hypotension is multifactorial and depends on patient-related factors, as well as on complications related to the dialysis procedure. The main causes Intradialytic hypotension have been reported to be acute hypovolemia during ultrafiltration and inadequate compensatory mechanisms such as left ventricular dysfunction, inappropriate plasma refilling ,Impaired vasoconstriction induced by dysregulation of autonomic nervous system.
Diabetes mellitus is the most common cause of chronic renal failure .Diabetic patients are more prone to cardiovascular diseases than non-diabetics .Although diabetes is in relation with hypertension ,It is associated with autonomic neuropathy which contribute to intradialytic hypotension . Recent researches suggested that older age and long dialytic age may incease risk of intradialytic hypotension.
Dates
| Darrera verificació: | 02/28/2019 |
| Primer enviat: | 03/04/2019 |
| Inscripció estimada enviada: | 03/07/2019 |
| Publicat per primera vegada: | 03/11/2019 |
| Última actualització enviada: | 03/07/2019 |
| Publicació de l'última actualització: | 03/11/2019 |
| Data d'inici de l'estudi real: | 03/31/2019 |
| Data estimada de finalització primària: | 05/31/2019 |
| Data estimada de finalització de l’estudi: | 06/30/2019 |
Condició o malaltia
Intervenció / tractament
Diagnostic Test: glycated hemoglobin
Fase
Grups de braços
| Braç | Intervenció / tractament |
|---|---|
| diabetic patients suffer from diabetes mellitus | |
| non diabetic patients free from diabetes with normal blood glucose level |
Criteris d'elegibilitat
| Edats elegibles per estudiar | 18 Years Per a 18 Years |
| Sexes elegibles per estudiar | All |
| Mètode de mostreig | Non-Probability Sample |
| Accepta voluntaris saludables | Sí |
| Criteris | Inclusion Criteria: All haemodialysed end stage kidney disease patients of the haemodialysis unit in Assiut health insurance hospital Exclusion Criteria: - 1-Advanced heart failure 2-Clinical instability requiring hospital admission. 3-History of alcohol or substance abuse 4-previous history of psychotic disorders |
Resultat
Mesures de resultats primaris
1. the correlation between diabetes and intradialytic hypotension [4 weeks]
2. the correlation between dialytic age and intradialytic hypotension [4 weeks]
