Fluid Infusion During Breast Surgery
Paraules clau
Resum
Descripció
The optimal amount and type of fluid given during surgery has not been defined. It has been agreed that hypovolemia must be avoided, but at the same time it has been agreed that fluid excess is harmful for organ function.When distributing fluids it is usually either crystalloids og colloids which are given. The effects of the two types of fluid have not been compared. Our hypothesis is that using a colloid (HES 130/0,4) will improve orthostatic function, nausea/vomiting and shorten hospital stay, compared to using a crystalloid (Lactated Ringer's solution).The amount of fluid the patient receives, will be individually tailored by monitoring SV using esophageal Doppler technique during surgery.
Dates
| Darrera verificació: | 01/31/2009 |
| Primer enviat: | 02/04/2007 |
| Inscripció estimada enviada: | 02/04/2007 |
| Publicat per primera vegada: | 02/05/2007 |
| Última actualització enviada: | 02/26/2009 |
| Publicació de l'última actualització: | 03/02/2009 |
| Data d'inici de l'estudi real: | 03/31/2009 |
| Data estimada de finalització primària: | 08/31/2009 |
| Data estimada de finalització de l’estudi: | 08/31/2009 |
Condició o malaltia
Intervenció / tractament
Drug: Hydroxyethylstarch 130/0,4
Drug: Lactated Ringer's solution
Fase
Criteris d'elegibilitat
| Edats elegibles per estudiar | 18 Years Per a 18 Years |
| Sexes elegibles per estudiar | All |
| Accepta voluntaris saludables | Sí |
| Criteris | Inclusion Criteria: - Patients having performed elective breast surgery. - Age between 18 and 70 years - Patients who have given written consent to participate in the project after haven completely understood the contents and limitations of the protocol. Exclusion Criteria: - Patients who do not understand or speak Danish - Patients who have not signed the informed consent or the written authority - pre-medication, except 1g paracetamol - ASA > II - Pregnant or breastfeeding - Known to have Renal disease - Known to have Psychiatric disorder (not considering the use of SSRI antidepressive) - Need for crash induction or prone position. - Oesophageal varicoses - Necrosis or cancer in: Mouth, Pharynx, Larynx or Oesophagus - Coarctation or aneurism in the proximal Aorta - Severe bleeding disease |
Resultat
Mesures de resultats primaris
1. To investigate orthostatic function, measured by Finapress [undefined]
Mesures de resultats secundaris
1. To investigate the occurrence of postsurgery nausea/vomiting. [undefined]
2. To investigate the amount of time until discharge criteria from the Postanaesthetic Care Unit have been achieved. [undefined]
3. To investigate balance function, measured by BalanceMaster [undefined]
