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Panniculitis is a group of diseases whose hallmark is inflammation of subcutaneous adipose tissue (the fatty layer under the skin – panniculus adiposus). Symptoms include tender skin nodules, and systemic signs such as weight loss and fatigue.

Restated, an inflammatory disorder primarily localized in the subcutaneous fat is termed a 'panniculitis', a group of disorders that may be challenging both for the clinician and the dermatopathologist. The general term for inflammation of any adipose tissue ...