Holostemma is a genus of flowering plants in the family Apocynaceae. The genus was first described in 1810. As presently constituted, the genus contains only one known species, Holostemma ada-kodien, native to southern Asia (China, Nepal, Pakistan, Kashmir, India, Sri Lanka, Myanmar, Thailand).
formerly includedHolostemma chilense, syn of Cynanchum chilense
Holostemma laeve, syn of Vincetoxicum laeve
Holostemma pictum, syn of Graphistemma pictum
Holostemma sinense, syn of Metaplexis hemsleyana
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