National Institute of Diabetes and Digestive and Kidney Diseases 2012
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury
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Resum
Crofelemer is an antidiarrheal agent derived from the red sap of the South American plant Croton lechleri, which is used to treat noninfectious diarrhea in HIV positive patients on antiretroviral therapy. Crofelemer is associated with occasional instances of serum enzyme elevations during therapy, but has not been linked to cases of clinically apparent acute liver injury.
