7 resultats
OBJECTIVE
To investigate the inhibitory effect of Boschniakia rossica(BR) on hepatocarcinogenesis in rats.
METHODS
Based on immunohistochemistry techniques, the expression of placental form glutathione S-transferase(GST-P), mutant p53 and p21 protein were investigated in hepatic preneoplastic
AIM:To investigate the effect of Boschniakia rossica (BR) extract on expression of GST-P, p53 and p21(ras) proteins in early stage of chemical hepatocarcinogenesis in rats and its anti-inflammatory activities.METHODS:The expression of tumor marker-placental form glutathione S-transferase (GST-P),
OBJECTIVE
To study the antioxidative effect of aqueous fraction of Boschniakia rossica(BR) extracted with methanol and fractionated with dichloromethane and water.
METHODS
Serum activities of superoxide dismutase(SOD), malondialdehyde(MDA), glutathione peroxidase (GSH-PX) and glutathione
The present study was undertaken to investigate the hepatoprotective effect of Boschniakia rossica extract (BRE), rich in phenylpropanoid glycoside and iridoid glucoside, on CCl(4)-induced liver damage. Male Wistar rats were randomly divided into six groups of ten each. While the first group was
The protective effect of iridoid glucosides from Boschniakia rossica (BRI) against carbon tetrachloride (CCl4)-induced liver injury was examined. CCl4 at a dose of 0.5 ml/kg of body weight was given intraperitoneally to rats to induce liver damage. The rats were sacrificed 16 h after the CCl4
OBJECTIVE
To investigate the intervention effect of aqueous fractions from Boschniakia rossica (BRAF) on hepatic oxidative stress in mice with liver injury induced by carbon tetrachloride (CCl4).
METHODS
The experimental mice were randomly assigned into the normal control group, the model group, the
The protective effect of rossicaside B, the major phenylpropanoid glycoside from Boschniakia rossica, on CCl(4)-induced hepatotoxicity and the mechanisms underlying its protective effect were investigated. The mice were administered orally with rossicaside B (100 or 200 mg/kg of body weight) 48, 24