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Juvenile muscular atrophy of distal upper extremity associated with airway allergy: two cases successfully treated by plasma exchange.

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Juvenile muscular atrophy of the distal upper extremity (JMADUE) is postulated to be a type of flexion myelopathy. However, patients with typical clinical features of JMADUE but without evidence of flexion myelopathy have been reported. We recently reported a significant association of JMADUE with

Efficacy and Safety of Abicipar in Neovascular Age-Related Macular Degeneration: 52-Week Results of Phase 3 Randomized Controlled Study

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Purpose: To compare the efficacy and safety of abicipar every 8 weeks and quarterly (after initial doses) versus ranibizumab every 4 weeks in treatment-naïve patients with neovascular age-related macular degeneration (AMD).

Abicipar pegol: an investigational anti-VEGF agent for the treatment of wet age-related macular degeneration

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Introduction: Several approaches have been investigated for the management of wet age-related macular degeneration (w-AMD); however, the first-line treatment option for w-AMD currently constitutes anti-VEGF agents. Abicipar pegol is a designed ankyrin repeat

Abicipar pegol for neovascular age-related macular degeneration

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Introduction: The development of intravitreal anti-vascular endothelial growth factor (VEGF) therapy has revolutionized management of neovascular age-related macular degeneration (nAMD) and serves as the standard of care for treating this

Spontaneous spinal cerebrospinal fluid leaks as the cause of subdural hematomas in elderly patients on anticoagulation.

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Subdural hematoma is a relatively common complication of long-term anticoagulation, particularly in the elderly. The combination of anticoagulation and cerebral cortical atrophy is believed to be sufficient to explain the subdural bleeding. The authors report a series of elderly patients who were on

The impact of pollution on allergic disease.

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Evidence suggests that allergic disease is becoming more common, particularly in industrialized societies. Two studies of schoolchildren from Aberdeen, Scotland aged 8-13 years were undertaken in 1964 and 1989 using identical questionnaires, and found that the reported prevalence of asthma had risen

Outcome of patients with cedar asthma with continuous exposure.

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After an average follow-up of 6.5 yr (range 1 to 13), 48 of 48 patients with cedar asthma, who were still working in the same industry, were re-examined. In all of them, the diagnosis of cedar asthma had been confirmed with a specific challenge inhalation test with plicatic acid. We graded the

Histamine antagonist Bepotastine suppresses nasal symptoms caused by Japanese cedar and cypress pollen exposure.

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Objective: To determine the efficacy of the antihistamine bepotastine on treating nasal symptoms in patients with Japanese cedar and cypress pollinosis, based on two previous studies that looked at bepotastine OD's inhibitory effect on symptom onset after exposure. Design and methods: Randomized

Beneficial effects of leukotriene receptor antagonists in the prevention of cedar pollinosis in a community setting.

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BACKGROUND In recent years, many countries have experienced an increase in the prevalence of allergic rhinitis. No effective approach is currently available to prevent the onset of symptoms in allergic individuals. Pranlukast, a leukotriene receptor antagonist with a good safety and efficacy record

A respiratory survey of cedar mill workers. II. Influence of work-related and host factors on the prevalence of symptoms and pulmonary function abnormalities.

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The influence of certain work-related and host factors on the prevalence of respiratory symptoms and pulmonary function abnormalities in 405 red cedar workers and 187 control workers was examined. In cedar workers, but not in controls, the prevalence of chest symptoms increased with duration of

Clinical and socioeconomic features of subjects with red cedar asthma. A follow-up study.

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A follow-up study of 128 subjects with red cedar asthma was conducted to evaluate the clinical and socioeconomic impact of the disease in determining the working status of the subjects after the diagnosis was made. The results suggest that the severity of asthma is not the main determinant of

Effect of forest land use change on carbohydrates, physical soil quality and carbon stocks in Moroccan cedar area.

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The present work was conducted to evaluate the carbon storage potential of Moroccan cedar forest and its vulnerability to transformations through deforestation and overgrazing. The present study took place in the Middle Atlas where is the most beautiful of Moroccan cedar forest (Cedrus atlantica).

Longitudinal decline in lung function in patients with occupational asthma due to western red cedar.

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BACKGROUND There are few reports about longitudinal changes in lung function in asthmatic patients. Patients with asthma had a greater loss of lung function than normal healthy adults. To date, there have been no studies about the longitudinal changes in lung function in patients with occupational

An ecological study on air pollution: changes in annual ring growth of the Japanese cedar and prevalence of respiratory symptoms in schoolchildren in Japanese rural districts.

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The effect of air pollution caused by oil-fired electricity-generating stations on the annual ring growth of the Japanese cedar (Cryptomeria japonica, D. Don) and prevalence of respiratory symptoms in schoolchildren were investigated. By retrospective analysis the annual ring growth has been

Bepotastine besilate OD tablets suppress nasal symptoms caused by Japanese cedar pollen exposure in an artificial exposure chamber (OHIO Chamber).

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OBJECTIVE To investigate the efficacy and safety of bepotastine, we conducted a randomized, investigator-blind, placebo-controlled and parallel study to evaluate the allergic symptoms and the cognitive function of the subjects with Japanese cedar (JC) pollinosis in response to JC pollen exposure in

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