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eremophilenolide/ligularia
L'enllaç es desa al porta-retalls
10 resultats
Application of high-speed counter-current chromatography for the isolation of antiviral eremophilenolides from Ligularia atroviolacea.
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Ligularia is mainly distributed in the western regions of China. Most of the species have been traditionally used in folk medicine for the treatment of hepatitis B, asthma, hemoptysis and pulmonary tuberculosis. In our continuation of research on antiviral components from traditional Chinese
Eremophilenolides from Ligularia fischeri.
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The chemical investigation of Ligularia fischeri afforded three new eremophilenolides which were identified as 6 beta-methoxy-8 beta-hydroxy-eremophil-7(11)-en-12,8 alpha-olide, ligufischerin, and 6-oxo-8 beta-hydroxy-eremophil-7(11)-en-12,8 alpha-olide by 1D- and 2D-NMR spectra. In addition, six
Eremophilenolides and other constituents from the roots of Ligularia sagitta.
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Chemical investigation of the roots of Ligularia sagitta has resulted in the characterization of six eremophilenolides 6beta,8beta-dimethoxy-10beta-hydroxyeremophil-7(11)-en-12,8alpha-olide (1), 6beta-angeloyloxy-10beta-hydroxy-8beta-methoxyeremophil-7(11)-en-12,8alpha-olide (2),
Two new eremophilenolides from Ligularia lapathifolia.
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From the roots of Ligularia lapathifolia two new eremophilane-type sesquiterpenes have been isolated. Their structures were established as 3beta-angeloyloxy-8beta-hydroxy-6alpha,15beta-epoxy-eremophil-7(11)-en-12,8alpha-olide (1) and 8betaH-eremophil-3,7(11)-dien-12,8alpha (15,6alpha)-diolide (2) by
Cytotoxic sesquiterpenoids from Ligularia pleurocaulis.
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The phytochemical investigation of whole plants of Ligularia pleurocaulis led to isolation of five sesquiterpenoids, including an eremophilenolide dimer named biligupleurolide, along with eight known sesquiterpenoids. Their structures were determined by spectroscopic methods including 2D NMR
Eremophilane sesquiterpenes from Ligularia myriocephala.
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Five new eremophilenolides, 1beta-angeloyloxy-6beta,10beta-dihydroxy-8beta-methoxyeremophil-7(11)-en-8alpha,12-olide ( 1), 1beta-angeloyloxy-6beta,10alpha-dihydroxy-8alpha-methoxyeremophil-7(11)-en-8beta,12-olide ( 2), 1beta,6beta-diangeloyloxy-8beta,10beta-dihydroxyeremophil-(11)-en-8alpha,12-olide
Cytotoxic sesquiterpenes from Ligularia platyglossa.
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Four sesquiterpene lactones including an eremophilenolide dimer, named as biligulaplenolide, 1, 8beta-hydroxy-1-oxo-(14alpha,15alpha eremophil-7(11),9(10)-dien-12,8alpha-olide, 2, 1-hydroxy-2-oxo-(14alpha,15alpha eremophil-1(10),7(11),8(9)-trien-12,8-olide, 3, 4alpha,8beta,9alpha-trihydroxy-
Two new compounds from Ligularia dolichobotrys.
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Two new compounds, a stigmasterol (1) and an eremophilenolide (2), were isolated from Ligularia dolichobotrys (Diels) together with ten known sesquiterpenoids, two known triterpenes and five known sterols. Their structures were elucidated by spectroscopic methods (IR, MS, 1H, 13C and 2D NMR). In
Eremophilane-type sesquiterpenoids with diverse skeletons from Ligularia sagitta.
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Five new highly oxygenated eremophilane-type sesquiterpenoids, possessing C19 (1 and 2), C15 (3 and 4), and C14 (8) skeletons, along with eight known eremophilenolides were obtained from the aerial parts of Ligularia sagitta. The absolute configuration of 1 was assigned by X-ray diffraction analysis
3β-Acet-oxy-8β,10β-dihy-droxy-6β-meth-oxy-eremophil-7(11)-en-8,12-olide.
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The title compound, C(18)H(26)O(7), is an eremophilenolide which has been isolated from the plant Ligularia duciformis for the first time. The present study confirms the atomic connectivity assigned on the basis of (1)H and (13)C NMR spectroscopy. The mol-ecule contains three fused rings, two
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