The invention relates to the use of (1.alpha.,2.beta.,4.beta.,5.alpha.,7.beta.)-7-[(hydroxydi-2-thienylacetyl- )oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0.sup.2,4]nonane salts for preparing a pharmaceutical composition for the prevention and treatment of diseases associated with
FIELD OF THE INVENTION
This invention concerns substituted diaza-spiro-[4.4]-nonane derivatives having neurokinin antagonistic activity, in particular NK.sub.1 antagonistic activity, their preparation, compositions comprising them and their use as a medicine, in particular for the treatment and/or