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norathyriol/càncer

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Norathyriol suppresses skin cancers induced by solar ultraviolet radiation by targeting ERK kinases.

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Ultraviolet (UV) irradiation is the leading factor in the development of skin cancer, prompting great interest in chemopreventive agents for this disease. In this study, we report the discovery of norathyriol, a plant-derived chemopreventive compound identified through an in silico virtual screening

Norathyriol suppresses transformation in JB6 P+ cells by the inhibition of Akt.

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BACKGROUND Chemoprevention has been acknowledged as an important and practical strategy for the management of skin cancer. Norathyriol, a naturally occurring compound present in various plants, has a potent anticancer-promoting activity. OBJECTIVE The aim was to investigate the chemopreventive

Estrogen modulation properties of mangiferin and quercetin and the mangiferin metabolite norathyriol.

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Mango fruit contain many bioactive compounds, some of which are transcription factor regulators. Estrogen receptor alpha (ERα) and beta (ERβ) are two regulators of gene transcription that are important in a variety of physiological processes and also in diseases including breast cancer. We examined
The characterization, binding ability and inclusion complexation behavior of the inclusion complexes of norathyriol with β-cyclodextrin (β-CD) and its derivatives such as hydroxypropyl-β-cyclodextrin (HPβCD), sulfobutyl ether β-cyclodextrin (SBEβCD) and mono

Xanthone derivatives: new insights in biological activities.

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Xanthones or xanthen-9H-ones (dibenzo-gamma-pirone) comprise an important class of oxygenated heterocycles whose role is well-known in Medicinal Chemistry. The biological activities of this class of compounds are associated with their tricyclic scaffold but vary depending on the nature and/or
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