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substance dependence/obesitat

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Quality of Recovery After General or Spinal Anesthesia for Inguinal Hernia Repair

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Inguinal hernia repair is one of the most commonly performed operations worldwide. The recommended treatment is surgery, which has undergone important advances in the last two decades. Different anesthetic techniques have been proposed for carrying out such procedures, including local anesthesia,

Naltrexone for Antipsychotic-Induced Weight Gain

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Persons with severe mental illness (SMI) die, on average, 25 years earlier than the general population1. Most of this early mortality can be attributed to cardiovascular disease (CVD) and diabetes mellitus (DM), which are directly related to obesity. Obesity is a leading cause of preventable death

A Novel Anti-Obesity Drug Combination as a Pharmacotherapy for Cocaine Dependence

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Cocaine (COC) dependence is a significant public health concern. A widely effective pharmacotherapy has not yet been identified for COC dependence. Innovative strategies are needed to identify an effective pharmacotherapy for COC dependence. Testing medications effective for disorders that share

Long-term Phentermine Pharmacotherapy: An Investigation for Symptoms of Dependence, Cravings, or Withdrawal

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Effects of the D3 Antagonist GSK598809 on Food Reward and Reinforcement

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This novel compound is being developed for the treatment of substance dependence and potentially other impulse control disorders. This is an fMRI study designed to examine the behavioural and physiological effects of a single dose of novel compound on food reward and reinforcement in relation to

Aminophylline and Cognitive Function After Sevoflurane Anaesthesia

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One-hundred-eighty ASA I-II patients aged 18-55 years scheduled for elective ambulatory general surgery with a duration >1 h under general anaesthesia were enrolled in this double-blinded placebo-controlled randomised study after obtaining of the approval of Institutional Ethical Committee of

Child and Adolescent Trial for Cardiovascular Health (CATCH)

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BACKGROUND: Coronary atherosclerosis begins in childhood and is expressed in adulthood as angina pectoris, myocardial infarction, or sudden death. The earliest lesion in the vascular system is the fatty streak, characterized by an accumulation of lipids in the intima. These lesions are present in
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