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substance dependence/seizures

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rTMS Over the Supplementary Motor Area for Treatment-resistant Obsessive-compulsive Disorder.

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N consecutive treatment-resistant OCD outpatients, fulfilling all the inclusion criteria, will be recruited by each center involved in the study. To be included in the study all the patients must be aged between 18 and 65 yy and have to meet DSM-5 criteria for OCD with a Y-BOCS total score > or = 20

Exploring the Effects of Coenzyme Q10 on Bioenergetics Metabolism in Geriatric Bipolar Depression

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Research Design and Methods: Bipolar Depressed Subjects: The Bipolar Depressed group will consist of 10 subjects (for the purposes of this study we would like to be able to recruit up to 30 subjects, with the goal of getting 10 to complete the protocol), ages 55-89, meeting DSM IV-TR criteria for

Deep Low-Frequency Repetitive Transcranial Magnetic Stimulation for Cessation of Pathological Gambling

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Deep Low-Frequency Repetitive Transcranial Magnetic Stimulation for cessation of pathological gambling Introduction: Pathological gambling (PG) is characterized by a persistent pattern of continued gambling behavior despite its adverse consequences. PG is a chronic, progressive, male-dominated

Aminophylline and Cognitive Function After Sevoflurane Anaesthesia

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One-hundred-eighty ASA I-II patients aged 18-55 years scheduled for elective ambulatory general surgery with a duration >1 h under general anaesthesia were enrolled in this double-blinded placebo-controlled randomised study after obtaining of the approval of Institutional Ethical Committee of

Nicotinic Receptor Augmentation of SSRI Antidepressants

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Mecamylamine for the Treatment of Depression in SSRI-Treated Partial Responders A. Purpose 1. To compare the nicotinic receptor antagonist mecamylamine (MEC) to placebo for the treatment of depressive symptoms in nicotine-dependent, cigarette smokers and in non-smokers who are maintained on, and are

Impact of Low Dose Naloxone on Fentanyl Requirements in Pediatric ICU Patients

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Objective: To determine if Naloxone administration to pediatric ICU patients on Fentanyl infusions require less Fentanyl compared to control patients. Background: During recent years there has been an increased awareness of the need for adequate sedation and analgesia of critically ill pediatric
The main outcome measure used is the SANS (Scale for the Assessment of Negative Symptoms. This is a semi strucutured interview which provides scores from 0-70. This is administered at baseline, week 2, 3, 5 and 6. Other outcome measures administered are (frequency mentioned above): PANSS (Positive
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