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triptolide/càncer
L'enllaç es desa al porta-retalls
5 resultats
Method of treating MYC-amplified tumors with RNA-polymerase II inhibitors
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Inicieu sessió / registreu-vos
FIELD OF THE INVENTION
The invention relates generally to the field of cancer treatment. More particularly, the invention relates to systems and methods for assessing whether a tumor over-expresses or over-amplifies c-Myc and, if it does, inhibiting the biologic activity of RNA polymerase II (pol
C14-hydroxyl esterified amino acid derivative of triptolide, and preparation method and use thereof
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a U.S. national stage filing, under 35 U.S.C .sctn. 371 (c), of International Application No. PCT/CN2015/093161, filed on Oct. 29, 2015. The entire contents of the aforementioned application are incorporated herein by reference.
TECHNICAL
Combined therapy of diterpenoid triepoxides and death domain receptor ligands for synergistic killing of tumor cells
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BACKGROUND
The cellular growth of normal tissue is maintained in homeostasis. This balance is determined by cellular proliferation and renewal on one hand, and cell death on the other. Neoplasia can result from aberrant regulation of this homeostasis, through somatic genetic abnormalities that cause
Triptolide derivatives and preparation method and use thereof
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Inicieu sessió / registreu-vos
TECHNICAL FIELD
The present invention relates to the pharmaceutical field, and more particularly triptolide derivatives, a method for preparing the same and a use thereof.
BACKGROUND
Thunder god vine, a woody vine of Celastraceae Tripterygium, is distributed at the south of Yangtze River or
Anticancer treatment using triptolide prodrugs
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Inicieu sessió / registreu-vos
FIELD OF THE INVENTION
The present invention relates to anticancer treatment using compounds which are water-soluble prodrugs of triptolide or its derivatives.
BACKGROUND OF THE INVENTION
Although many cancers can be cured by surgical resection, chemotherapy is often used as an adjunct to surgical
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