A method for treating a tumor is provided, which comprises the steps of preliminarily immunizing a patient in need of antitumor treatment with a toxin or toxin surrogate vaccine in an amount which is effective to generate an immune response to the toxin in the patient, thereby providing systemic protection from the toxin to the patient, and subsequently administering the toxin to the patient in an amount which is effective to kill tumor cells. The toxin may be any suitable toxin, for example ricin, abrin, gelonin or diphtheria.

Novavax, Inc.

Method for treating tumors with a toxin

Certain toxic compounds (T) such as, for example, compounds based upon diphtheria toxin, ricin toxin, pseudomonas exotoxin, .alpha.-amanitin, pokeweed antiviral protein (PAP), ribosome inhibiting proteins, especially the ribosome inhibiting proteins of barley, wheat, corn, rye, gelonin and abrin, as well as certain cytotoxic chemicals such as, for example, melphalan and daunomycin can be conjugated to certain analogs of gonadotropin-releasing hormone to form a class of compounds which, when injected into an animal, destroy the gonadotrophs of the animal's anterior pituitary gland. Hence such compounds may be used to sterilize such animals and/or to treat certain sex hormone related diseases.

Colorado State University Research Foundation

Method for treating cancer

Compositions and methods of treatment comprising the lectins Abrin and Abrus agglutinin for the suppression of post-surgical malignant tumor metastasis are disclosed. Also disclosed is the administration of compositions and methods of treatment utilizing the above lectins in combination with either or both radiation treatment and/or chemotherapy.

abrin/rakovina

Method for treating tumors with a toxin

Method for treating tumors with a toxin

Method for treating cancer

Orally administrable anti-metastatic lectin compositions and methods

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