Single lot of Andrographis paniculata (AP) concentrated granules (Andrographis Herba) will be manufactured by Nong's Company Limited under GMP standard

Squamous Cell Carcinoma of Esophagus

Andrographis Paniculata

Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong

The Effect of Andrographis Paniculata (AP) on Palliative Management of Advanced Esophageal Cancer

Symptomatic relief of Dysphagia and quality of life after treatment Dysphagia measured by Dysphagia score Quality of Life measured by EORTC-QLQ-C30

Difficulty to swallow by dysphagia grade 0 = able to eat normal diet / no dysphagia.
= able to swallow some solid foods
= able to swallow only semi solid foods
= able to swallow liquids only
= unable to swallow anything / total dysphagia

Side effects related to AP including
Gastrointestinal upset
Nausea and Vomiting
Allergy
Diarrhoea
Abdominal pain
Dizziness

Philip Wai Yan Chiu

Professor

Chinese University of Hong Kong

1 - Active comparator, consisted of 30 adult patients with active Rheumatoid Arthritis, randomly assigned, taking the active product, in addition to base medication (Mtx + Pdn)

2 - Placebo comparator, consisted of 30 adult patients with active Rheumatoid Arthritis, randomly assigned, taking the placebo formulation, in addition to base medication (Mtx + Pdn)

Arthritis, Rheumatoid

Andrographolide formula Oral tablets, 30mg, three times per day, during a total of 105 continuous days.

FANG(30)

Placebo 30mg tabs, 3/day, 105 days continuously.

Placebo

Government of Chile - Science and Technology Development Fund (Study main sponsor)

andrographis serpyllifolia/rakovina

The Effect of Andrographis Paniculata (AP) on Palliative Management of Advanced Esophageal Cancer

Efficacy Study of FANG(30) for Active Rheumatoid Arthritis in Adult Patients

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