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Calcium phosphate cements have received widespread attention for their possible role as bone-grafting material and bone fillers in skeletal defects. They were evaluated as a biomaterial in many aspects. No serious harmful effects such as foreign body reaction and tissue necrosis against to calcium
Case: We report on 2 patients who developed avascular necrosis (AVN) of the talus and poor patient outcomes after undergoing calcium phosphate injection into talar dome bone marrow lesions.
Conclusion:
OBJECTIVE
To introduce a new method using calcium phosphate cement/Danshen drug delivery system for avascular necrosis of femoral head and to evaluate its clinical outcome.
METHODS
From May 2000 to June 2005, 48 patients (54 hips) with avascular necrosis of femoral head were treated with calcium
OBJECTIVE
To introduce a new method using calcium phosphate cement/Danshen drug delivery system for treating ischemic necrosis of the femoral head and evaluate its curative effect.
METHODS
From May 2000 to June 2005, 48 adult patients (54 hips) with ischemic necrosis of the femoral head at Stages I,
The application of nanotechnology for in medicine is developing rapidly, thereby increasing human exposure to nanomaterials and significantly so. A rising question is the biosecurity of nanoparticles (NPs). Although calcium phosphate (CaP) phase is biocompatible and biodegradable, many in vitro
Avascular necrosis of the femoral head (ANFH) is difficult to treat due to high pressure and hypoxia, and reduced levels of growth factors such as bone morphogenetic protein (BMP), and vascular endothelial growth factor (VEGF). We generated a novel calcium phosphate (CPC) composite scaffold, which
Subchondral and articular collapse following nontraumatic osteonecrosis of the femoral head is an important cause of osteoarthritis in patients between ages 20 and 40. Because hip arthroplasty in the younger population is prone to early wear and failure, it is paramount to prevent collapse once
OBJECTIVE
To study the mechanism of compound of calcium phosphate (TCP) and platelet-rich plasma(PRP) in the treatment of femoral head necrosis.
METHODS
The left femoral heads of 48 New Zealand white rabbits were frozen by liquid nitrogen as to make the model of femoral head necrosis. Twenty-four
BACKGROUND
Calciphylaxis is a rare condition of rapidly extending ischemic skin necrosis or acral gangrene of fingers, toes or penis in patients with chronic renal failure. It may be accompanied by extensive metastatic calcification of soft tissues. Histology of infarcted tissues shows prominent
OBJECTIVE
Basic calcium phosphate (BCP) crystals (octacalcium phosphate (OCP), carbapatite (CA) and hydroxyapatite (HA)) are associated with severe forms of osteoarthritis. In advanced osteoarthritis, cartilage shows chondrocyte apoptosis, overexpression of annexin 5 (A5) and BCP crystal deposition
OBJECTIVE
Calcium phosphate activity coating containing different contents of zinc was deposited onto the surface of pure titanium modified by plasma electrolytic oxidation. The physical and chemical properties of different contents of zinc were compared among three groups, and the influence on
In this report, the hybrid calcium phosphate (CaP) nanoparticles were synthesized and functionalized with Newcastle disease virus (NDV). These nanoparticles were synthesized by a combination of co-precipitation and polymerization process and functionalized with amino propyl triethoxy silane before
BACKGROUND
Vertebroplasty was developed to mechanically reinforce weakened vertebral bodies. Polymethylmethacrylate (PMMA) bone cement has been most commonly used but carries risks of thermal injury and respiratory and cardiovascular complications. Calcium phosphate (CaP) offers the potential for
Dendritic cells (DCs) are essential for initiating and directing antigen-specific T-cell responses. Genetic modification of DC is under study for cancer immunotherapy, vaccine development, and antigen-targeted immunosuppression. Adenovirus (Ad) type 5 (Ad5)-mediated gene transfer to mouse bone