glaucoma/protease

Odkaz je uložen do schránky

Vyberte typ řazení

Strana 1 z 58 Výsledek

Alteration of the serine protease PRSS56 causes angle-closure glaucoma in mice and posterior microphthalmia in humans and mice.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Angle-closure glaucoma (ACG) is a subset of glaucoma affecting 16 million people. Although 4 million people are bilaterally blind from ACG, the causative molecular mechanisms of ACG remain to be defined. High intraocular pressure induces glaucoma in ACG. High intraocular pressure traditionally was

Single nucleotide polymorphisms of metabolic syndrome-related genes in primary open angle glaucoma.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

OBJECTIVE To analyze single nucleotide polymorphisms (SNP) of primary open angle glaucoma- and metabolic syndrome-related genes in primary open angle glaucoma (POAG), in order to elucidate the roles of metabolic syndrome as a risk factor in POAG progress. METHODS SNP genotypes and alleles of

Extracellular proteases and neuronal cell death.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Neuronal cell death occurs during development of the central nervous system as well as in pathological situations such as acute injury and progressive degenerative diseases. For instance, granule cells in the developing cerebellum and neuronal precursor cells in the cortex undergo programmed cell

Secreted leukocyte protease inhibitor is present in aqueous humours from cataracts and other eye pathologies.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Previous studies identified serine, cysteine and metalloproteases in normal aqueous humours (AH) and suggested that a balance between proteases and their inhibitors may play a role in the modulation of the AH outflow. We aimed to determine whether secretory leukocyte protease inhibitor (SLPI), a

Heat shock proteins, immunity and glaucoma.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Glaucoma is no longer viewed simply as elevated intraocular pressure (IOP) that damages the optic nerve. In addition to high IOP, evidence is rapidly accumulating that suggests damage to the optic nerve may be initiated or sustained by any number of factors including ischemia, excitotoxicity,

Synthetic Polyclonal-Derived CDR Peptides as an Innovative Strategy in Glaucoma Therapy.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

The pathogenesis of glaucoma is strongly associated with the occurrence of autoimmune-mediated loss of retinal ganglion cells (RGCs) and additionally, recent evidence shows that specific antibody-derived signature peptides are significantly differentially expressed in sera of primary-open angle

Potential drug delivery approaches for XFS-associated and XFS-associated glaucoma.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Key tissue targets in treating exfoliation syndrome (XFS) and the associated glaucoma include lens, iris, and ciliary body, which produce the exfoliative material, and the trabecular meshwork, which may be impaired by the exfoliative material. In addition to antiglaucoma drug therapy, strategies for

Proteases in eye development and disease.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

The eye is one of the classical systems in developmental biology. Furthermore, diseases of the eye, many of which have a developmental basis, have devastating effects that often result in blindness. Proteases have diverse roles in ocular physiology and pathophysiology. Here, a broad overview is

Neuroprotection in glaucoma using calpain-1 inhibitors: regional differences in calpain-1 activity in the trabecular meshwork, optic nerve and implications for therapeutics.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Glaucoma is a group of irreversible blinding eye diseases affecting over 70 million people worldwide. Systemic delivery of calpain-1 inhibitors was proposed as a neuroprotection strategy for the prevention of progressive optic nerve damage in glaucoma. We present a general review of calpain-1 and an

Tissue differential microarray analysis of dexamethasone induction reveals potential mechanisms of steroid glaucoma.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

OBJECTIVE To identify myocilin (TIGR/MYOC) properties that are specific to the human trabecular meshwork (HTM). To search for genes highly expressed in dexamethasone (DEX)-induced HTM cells that are barely expressed or absent in DEX-induced cells from other tissues. METHODS TIGR/MYOC induction by

Aqueous humor protein dysregulation in primary angle-closure glaucoma.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

OBJECTIVE Primary angle-closure glaucoma (PACG) is associated with increased intraocular pressure, optic nerve damage, and progressive vision loss, but the molecular mechanism that underpins retinal ganglion neuropathy in PACG remains poorly understood. To better understand the pathogenesis of human

Apoptosis of retinal ganglion cells in glaucoma: an update of the molecular pathways involved in cell death.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Apoptosis is a genetically controlled form of cell death that ganglion cells undergo during normal development of the retina and in diseases affecting the optic nerve, such as glaucoma. This mechanism of cell death is controlled by specific genes and their products that are activated in the dying

Cystatin a, a potential common link for mutant myocilin causative glaucoma.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Myocilin (MYOC) is a 504 aa secreted glycoprotein induced by stress factors in the trabecular meshwork tissue of the eye, where it was discovered. Mutations in MYOC are linked to glaucoma. The glaucoma phenotype of each of the different MYOC mutation varies, but all of them cause elevated

Glaucoma: ocular Alzheimer's disease?

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Glaucoma is a chronic neurodegeneration of the optic nerve and one of the leading causes of vision loss in the world among the aging. Retinal ganglion cells (RGCs) have been shown to die by apoptosis, or programmed cell death. Central to apoptosis is the activation of specific proteases, termed

Glaucoma is associated with plasmin proteolytic activation mediated through oxidative inactivation of neuroserpin.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Neuroserpin is a serine protease inhibitor that regulates the activity of plasmin and its activators in the neuronal tissues. This study provides novel evidence of regulatory effect of the neuroserpin on plasmin proteolytic activity in the retina in glaucoma. Human retinal and vitreous tissues from

Předchozí
1
2
3
4
další

Připojte se k naší
facebookové stránce

Herbal & Natural Medicine

Nejúplnější databáze léčivých bylin podložená vědou

Funguje v 55 jazycích
Bylinné léky podporované vědou
Rozpoznávání bylin podle obrázku
Interaktivní mapa GPS - označte byliny na místě (již brzy)
Přečtěte si vědecké publikace související s vaším hledáním
Hledejte léčivé byliny podle jejich účinků
Uspořádejte své zájmy a držte krok s novinkami, klinickými testy a patenty

Zadejte symptom nebo chorobu a přečtěte si o bylinách, které by vám mohly pomoci, napište bylinu a podívejte se na nemoci a příznaky, proti kterým se používá.
* Všechny informace vycházejí z publikovaného vědeckého výzkumu