mimosine/nekróza

Odkaz je uložen do schránky

ČlánkyKlinické testyPatenty

Vyberte typ řazení

Strana 1 z 16 Výsledek

Mimosine-induced cell death and related chromatin changes.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

The non-protein amino acid mimosine has recently been shown to induce an unusual mode of cell death that differs from necrosis and apoptosis, the two fundamental schemes of cell death. The drug affects primarily the cell nucleus and induces first condensation of the chromatin into a regular network

Iron-mediated H2O2 production as a mechanism for cell type-specific inhibition of tumor necrosis factor alpha-induced but not interleukin-1beta-induced IkappaB kinase complex/nuclear factor-kappaB activation.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Coordinated and specific regulation of tumor necrosis factor (TNF) and interleukin (IL)-1 signaling pathways and how and whether they are modified by different agents are key events for proper immune responses. The IkappaB kinase complex (IKK)/NF-kappaB and JNK/AP-1 pathways are central mediators of

Effect of the compound L-mimosine in an in vivo model of chronic granuloma formation induced by potassium permanganate (KMNO4).

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

The plant amino acid L-mimosine has recently been suggested to inhibit cells at a regulatory step in late G1 phase before establishment of active DNA replication forks. In addition, L-mimosine is an extremely effective inhibitor of DNA replication in chromosomes of mammalian nuclei. In this work,

Mimosine, a naturally occurring drug interfering primarily with the cell nucleus.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

The non-proteinogen aminoacid mimosine interfered seriously with cultured carp hepatocytes when added to the culture medium for 6 h in a concentration of 0.1 M. Cell transformation started with condensation of the chromatin into an unusual network of fibrils and segregation of the reticulate

Effects of Prolyl Hydroxylase Inhibitor L-mimosine on Dental Pulp in the Presence of Advanced Glycation End Products.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

BACKGROUND Proangiogenic prolyl hydroxylase (PHD) inhibitors represent a novel approach to stimulate tissue regeneration. Diabetes mellitus involves the accumulation of advanced glycation end products (AGEs). Here we evaluated the impact of AGEs on the response of human pulp tissue to the PHD

Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Survivin is a member of the inhibitor of apoptosis proteins that is expressed at high levels in most human cancers and may facilitate evasion from apoptosis and aberrant mitotic progression. Naturally occurring dietary compounds such as resveratrol have gained considerable attention as cancer

Angiopoietin-like 4 production upon treatment with hypoxia and L-mimosine in periodontal fibroblasts.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

A key factor in the modulation of angiogenesis as well as in bone resorption is angiopoietin-like 4. However, the role of angiopoietin-like 4 in periodontal tissue is unknown. Here, we hypothesized that hypoxia and the hypoxia mimetic agent L-mimosine can induce the production of

K562 cells display different vulnerability to H₂O₂ induced oxidative stress in differing cell cycle phases.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Oxidative stress can be defined as the increase of oxidizing agents like reactive oxygen and nitrogen species, or the imbalance between the antioxidative defense mechanism and oxidants. Cell cycle checkpoint response can be defined as the arrest of the cell cycle functioning after damaging chemical

Inhibiting survivin expression enhances TRAIL-induced tumoricidal activity in human hepatocellular carcinoma via cell cycle arrest.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Human Hepatocellular carcinoma (HCC) cell types exhibit a major resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell death, and the key determinants of mechanisms accounting for TRAIL susceptibility, still remain controversial. Our previous studies showed that

Induction of cell death by cytokines in cell cycle-synchronous tumor cell populations restricted to G1 and G2.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

In the present work, cytokine-mediated induction of cell death was investigated by flow cytometry in cell cycle-synchronous human tumor cell populations gained by centrifugal elutriation or by cell cycle blockade with mimosine and aphidicolin. Attention was payed to the question of whether the

Latent HIV-1 reactivation in transgenic mice requires cell cycle -dependent demethylation of CREB/ATF sites in the LTR.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

OBJECTIVE We previously produced a line of transgenic mice that carried the HIV-1 genome deficient in the gene. Although the HIV-1 genome in the lymphocytes was dormant under normal physiological conditions, it could be reactivated by lipopolysaccharide (LPS) administration via induction of

Suppressive effects of Mimosa pudica (L.) constituents on the production of LPS-induced pro-inflammatory mediators.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

The present study deals with the isolation of fourteen compounds from the active ethyl acetate (MPE) extract of M. pudica (L.) whole plant and their subsequent evaluation for the nitric oxide (NO), tumor necrosis factor alpha (TNF-α) and interleukin 1 beta (IL-1ß) inhibitory activities in

Hsp25-induced radioresistance is associated with reduction of death by apoptosis: involvement of Bcl2 and the cell cycle.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

We previously demonstrated the protective effect of the small heat-shock protein against oxidative damage induced by tumor necrosis factor alpha. Here we have extended our studies of the possible role of Hsp25 in ionizing radiation-induced damage. For these studies, we transfected murine fibroblast

The Influence of Pro-Inflammatory Factors on Sclerostin and Dickkopf-1 Production in Human Dental Pulp Cells Under Hypoxic Conditions.

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

Sclerostin (Sost) and dickkopf (Dkk)-1 are inhibitors of the Wnt signaling pathway that plays a role in regenerative processes. Hypoxia-based strategies are used for regenerative approaches, but the influence of hypoxia on Sost and Dkk-1 production in a pro-inflammatory environment is unclear. The

[The virulence of L. leucocephala for goats in northeastern Mexico].

Články mohou překládat pouze registrovaní uživatelé

Přihlášení Registrace

When fed 100% Leucaena during a period of 45 days goats with experience in L.-fodder took significantly (P less than 0.05) more dry matter (50.01 g/kg0.75) than those without or only possible experience (44.40 g/kg0.75 and 45.63 g/kg0.75). The uptake of Mimosine from animals with Mimosine experience

Předchozí
1
2
další

Připojte se k naší
facebookové stránce

Herbal & Natural Medicine

Nejúplnější databáze léčivých bylin podložená vědou

Funguje v 55 jazycích
Bylinné léky podporované vědou
Rozpoznávání bylin podle obrázku
Interaktivní mapa GPS - označte byliny na místě (již brzy)
Přečtěte si vědecké publikace související s vaším hledáním
Hledejte léčivé byliny podle jejich účinků
Uspořádejte své zájmy a držte krok s novinkami, klinickými testy a patenty

Zadejte symptom nebo chorobu a přečtěte si o bylinách, které by vám mohly pomoci, napište bylinu a podívejte se na nemoci a příznaky, proti kterým se používá.
* Všechny informace vycházejí z publikovaného vědeckého výzkumu