3 Výsledek
OBJECTIVE
To determine the safety and efficacy of intravenously administered phytonadione (vitamin K1) in patients on routine oral warfarin anticoagulation.
METHODS
This retrospective cohort study comprised adults who were taking warfarin, were not bleeding, and received intravenous phytonadione
Parenteral vitamin K1 (phytonadione) is used for anticoagulant reversal, and a boxed warning exists with intravenous and intramuscular administration due to the possibility of severe reactions, including fatalities. These reactions resemble hypersensitivity or anaphylaxis, including anaphylactoid
OBJECTIVE
A potential interaction involving therapeutic doses of ascorbic acid and warfarin is described.
CONCLUSIONS
A 65-year-old Caucasian man with chronic cardiac and pulmonary disorders was admitted to the emergency room for chest pain, shortness of breath, nausea, and diaphoresis. Imaging