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prolidase deficiency/proline
Odkaz je uložen do schránky
Strana 1 z 61 Výsledek
Collagen biosynthesis anomalies in prolidase deficiency: effect of glycyl-L-proline on the degradation of newly synthesized collagen.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Prolidase deficiency is a rare hereditary disease characterized by an iminodipeptiduria especially composed by glycyl-L-proline which is not further degraded. The study of collagen metabolism in fibroblast cultures from three prolidase-deficient patients showed an increase in the rapidly degraded
[Effective therapy with a glycine-proline ointment in a patient with recurrent ulcers from prolidase deficiency].
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
BACKGROUND
Prolidase deficiency is a rare disease. Lower leg recalcitrant ulcerations are the most characteristic symptoms.
METHODS
Woman diagnosed of prolidase deficiency with leg recalcitrant and infected ulcerations. Dermatology service solicits a proline and glycline containing ointment after
Human prolidase and prolidase deficiency: an overview on the characterization of the enzyme involved in proline recycling and on the effects of its mutations.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Here we summarized what is known at the present about function, structure and effect of mutations in the human prolidase. Among the peptidases, prolidase is the only metalloenzyme that cleaves the iminodipeptides containing a proline or hydroxyproline residue at the C-terminal end. It is relevant in
Normal hydroxylation of proline in collagen synthesized by skin fibroblasts from a patient with prolidase deficiency.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The extent of hydroxylation of proline in collagen synthesized and secreted into the culture medium by skin fibroblasts derived from a patient with prolidase deficiency has been examined and found to be normal. It would seem likely that to a considerable extent the urinary proline-containing
Prolidase deficiency: the use of topical proline for treatment of leg ulcers.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
A 41-year-old man with prolidase deficiency has had chronic leg ulcers and recurrent cellulitis for most of his life. Until recently he had been hospitalized at least annually for this and suffered significant morbidity as a result. Since commencing topical 5% proline in white soft paraffin ointment
Effect of topical application of glycine and proline on recalcitrant leg ulcers of prolidase deficiency.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Topical proline therapy in prolidase deficiency.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Liquid chromatography-mass spectrometry for simultaneous analyses of iminodipeptides containing an N-terminal or a C-terminal proline.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Simultaneous analyses of synthetic iminodipeptides containing an N-terminal proline or a C-terminal proline have been demonstrated using liquid chromatography-mass spectrometry with an atmospheric pressure ionization interface system. The separation of iminodipeptides was carried out on a
N-benzyloxycarbonyl-L-proline: an in vitro and in vivo inhibitor of prolidase.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Prolidase deficiency (PD) is a recessive disorder of the connective tissue caused by mutations in the prolidase, a specific peptidase, cleaving the dipeptides with a C-terminal prolyl and hydroxyprolyl residue. PD is a complex syndrome characterized mainly by intractable skin lesions, recurrent
Liquid chromatography-mass spectrometry for the qualitative analyses of iminodipeptides in the urine of patients with prolidase deficiency.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Analyses of standard iminodipeptides and iminodipeptides in the urine of patients with prolidase deficiency have been demonstrated using liquid chromatography-mass spectrometry with an atmospheric pressure ionization interface system. The separation was carried out on a reversed-phase column using
Prolidase deficiency in two dermatological patients in western Sicily.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Prolidase deficiency is a rare disorder inherited through an autosomal recessive gene. The hallmark of the disorder are iminodipeptiduria, chronic skin ulcers, recurring infections, mental retardation and characteristic facial appearance, although prolidase deficiency can occur with no clinical
Normal production, nature, and extent of intracellular degradation of newly synthesized collagen in fibroblasts from a patient with prolidase deficiency.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
We have examined the extent of intracellular degradation of newly synthesized collagen occurring in fibroblasts from a patient with prolidase deficiency, a rare, autosomal recessively inherited disorder, in which a lack of prolidase, which normally cleaves imidodipeptides with a C-terminal Pro or
The use of liquid chromatography-mass spectrometry for the identification and quantification of urinary iminodipeptides in prolidase deficiency.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
It has been reported that the urine of patients with prolidase deficiency contains various iminodipeptides with a carboxyl-terminal proline (hydroxyproline). These iminodipeptides have hitherto been detected indirectly by acid hydrolysis or enzymatic digestion, followed by amino acid analysis. In
Measurement of iminodipeptides in the serum of patients with prolidase deficiency using liquid chromatography-mass spectrometry.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
Iminodipeptides containing C-terminal proline or hydroxyproline were determined in sera from patients with prolidase deficiency, in their mother's serum, and in the sera of unrelated controls, using liquid chromatography-mass spectrometry with an atmospheric pressure ionization interface system. The
The effects of serum iminodipeptides and prednisolone on superoxide generation and tyrosyl phosphorylation of proteins in neutrophils from a patient with prolidase deficiency.
Články mohou překládat pouze registrovaní uživatelé
Přihlášení Registrace
The aim of this study was to examine the effects of serum iminodipeptides and prednisolone on superoxide generation and tyrosyl phosphorylation of proteins in neutrophils from a patient with prolidase deficiency, and also to find the causative effects of superoxide on inflammatory skin lesions. When
Nejúplnější databáze léčivých bylin podložená vědou
- Funguje v 55 jazycích
- Bylinné léky podporované vědou
- Rozpoznávání bylin podle obrázku
- Interaktivní mapa GPS - označte byliny na místě (již brzy)
- Přečtěte si vědecké publikace související s vaším hledáním
- Hledejte léčivé byliny podle jejich účinků
- Uspořádejte své zájmy a držte krok s novinkami, klinickými testy a patenty
Zadejte symptom nebo chorobu a přečtěte si o bylinách, které by vám mohly pomoci, napište bylinu a podívejte se na nemoci a příznaky, proti kterým se používá.
* Všechny informace vycházejí z publikovaného vědeckého výzkumu
