Strana 1 z 101 Výsledek
1. FIELD OF THE INVENTION
The present invention relates to Pyrrole-Type compounds, compositions comprising Pyrrole-Type compounds, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a composition comprising a Pyrrole-Type compound. The compounds,
FIELD OF THE INVENTION
The present invention relates to Pyrrole-Type compounds, compositions comprising Pyrrole-Type compounds, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a composition comprising a Pyrrole-Type compound. The compounds,
1. FIELD OF THE INVENTION
The present invention relates to Pyrrole-Type compounds, compositions comprising Pyrrole-Type compounds, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a composition comprising a Pyrrole-Type compound. The compounds,
1. FIELD OF THE INVENTION
The present invention relates to Pyrrole-Type compounds, compositions comprising Pyrrole-Type compounds, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering a Pyrrole-Type compound. The compounds, compositions, and methods
BACKGROUND OF THE INVENTION
This invention relates to a pharmaceutical compound found particularly suitable for inhibiting growth of solid tumors of the colon or breast in warm blooded animals.
PRIOR ART
There has been a continuing search for treatment for solid cancer tumors of the colon or breast
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to 5H-thioeno(3,4-c)pyrrole-4,6-dione derivatives which are active as inhibitors of tumor necrosis factor (TNF) released by cells, the preparation of these derivatives, as well as their application as
FIELD OF THE INVENTION
The present invention is directed to compounds, methods, and compositions for the treatment of cancer, neurological disorders, and fibrotic disorders.
BACKGROUND
Every year, cancer claims the lives of more than half a million Americans. Cancer is the second leading cause of
FIELD OF THE INVENTION
The present invention is directed to compounds, methods, and compositions for the treatment of cancer, neurological disorders, and fibrotic disorders.
BACKGROUND
Every year, cancer claims the lives of more than half a million Americans. Cancer is the second leading cause of
FIELD OF THE INVENTION
The present invention is directed to compounds, methods, and compositions for the treatment of cancer, neurological disorders, and fibrotic disorders.
BACKGROUND
Every year, cancer claims the lives of more than half a million Americans. Cancer is the second leading cause of
FIELD OF THE INVENTION
The present invention is directed to compounds, methods, and compositions for the treatment of cancer, neurological disorders, and fibrotic disorders.
BACKGROUND
Every year, cancer claims the lives of more than half a million Americans. Cancer is the second leading cause of
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to 5H-thioeno(3,4-c)pyrrole-4,6-dione derivatives which are active as inhibitors of tumor necrosis factor (TNF) released by cells, the preparation of these derivatives, as well as their application as
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a U.S. National Stage Application pursuant to 35 U.S.C. .sctn.371 of International Patent Application PCT/EP2013/071445, filed on Oct. 14, 2013, and published as WO 2014/060366 on Apr. 24, 2014, which claims priority to European Patent
TECHNICAL FIELD
The present invention relates to a pyrrole-substituted indolone derivative or pharmaceutically acceptable salts thereof, a preparation method therefor, a composition comprising the same and use thereof. In particular, the present invention relates to a pyrrole-substituted indolone
BACKGROUND OF THE INVENTION
Cancer is the second leading cause of death in the United States, exceeded only by heart disease. (Cancer Facts and Figures 2004, American Cancer Society, Inc.) Despite recent advances in cancer diagnosis and treatment, surgery and radiotherapy may be curative if a cancer
BACKGROUND OF THE INVENTION
Although tremendous advances have been made in elucidating the genomic abnormalities that cause malignant cancer cells, currently available chemotherapy remains unsatisfactory, and the prognosis for the majority of patients diagnosed with cancer remains dismal. Most