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The associations between saturated fatty acid (SFA) consumption and risk of breast cancer (BC) remains inconclusive. Therefore, we conducted this meta-analysis to determine the quantitative relations between dietary SFA intake and incidence of BC.Literatures published up to April 2015 were
Little is known about the biochemical basis of the action of free fatty acids (FFA) on breast cancer cell proliferation and apoptosis. Here we report that unsaturated FFAs stimulated the proliferation of human MDA-MB-231 breast cancer cells, whereas saturated FFAs inhibited it and caused apoptosis.
The relationship between dietary fat and subsequent risk of breast cancer was studied in 3988 initially cancer-free Finnish women aged 20-69 y. During a follow-up period of 20 y, 54 breast-cancer cases were diagnosed. Risk of breast cancer was significantly inversely related to energy intake and
BACKGROUND
Studies in animals and geographic correlations across populations suggest that fatty acid intake may have a positive relationship with breast cancer risk, but analytic epidemiologic studies of fat intake have been less supportive. Adipose tissue analysis provides a more objective
BACKGROUND
Breast cancer is the second leading cause of cancer-related deaths among women in most industrialized countries. Most breast cancers are considered sporadic, with only 5-10% estimated to be due to inherited susceptibility. The objective of this paper is to provide an overview of the
The influence of nutrition on breast cancer prognosis is still inconclusive and therefore dietary interventions incorporating dietary biomarkers are needed to confirm compliance with dietary goals and clarify biological mechanisms. The present study assessed whether a lifestyle This review presents current knowledge of diet and breast cancer. In the first part it reviews current knowledge of nutritional risk factors. Obesity, total energy intake, intake of saturated fatty acids and alcohol were considered as high risk factors for breast cancer in the past. In addition to
To investigate association between breast cancer risk and nutrients intake in Korean women, a case-control study was carried out, at Seoul, Korea. Incident cases (n=224) were identified through the cancer biopsy between February 1999 and December 2000 at two University hospitals in Seoul.
BACKGROUND
Breast cancer is a disease with diverse clinical symptoms, molecular profiles, and its nature to response its therapeutic treatments. Radiotherapy (RT), along with surgery and chemotherapy is a part of treatment in breast cancer. The aim of present study was to investigate pre and post
HER2/neu-positive breast cancer cells have recently been shown to use a unique Warburg-like metabolism for survival and aggressive behavior. These cells exhibit increased fatty acid synthesis and storage compared to normal breast cells or other tumor cells. Disruption of this synthetic process
French authorities are considering the implementation of a simplified nutrition labelling system on food products to help consumers make healthier food choices. One of the most documented candidates (Five-Colour Nutrition Label/Nutri-score) is based on the British Food Standards Agency Nutrient
To elucidate the effects of nutritional factors on regional differences in breast cancer mortality in Japan, the statistical analysis was made using the results of the national nutrition surveys in 12 districts from 1966 to 1980 and age-adjusted mortality from breast cancer from 1966 to 1990. The
Since unsaturated fatty acids have been shown to control cell division experimentally the fatty acid composition in human mammary cancers as compared with the healthy surrounding tissue was studied. Both phospholipid and neutral lipid fractions were extracted for study and further lipid peroxidation
OBJECTIVE
To examine the association between breast cancer risk and the fatty acid composition of phospholipids in prediagnostic serum samples.
METHODS
We analyzed the fatty acid composition in 130 incident postmenopausal breast cancer cases and 257 matched controls nested within the beta-Carotene
Five fatty acids, two saturated--palmitic (C16:0), stearic (C18:0), and three unsaturated--oleic (C18:1), linoleic (C18:2) and arachidonic (C20:4) were assayed in red cell membranes of breast cancer patients and healthy controls. No significant difference in the levels of saturated fatty acids was