lesser/antiinflammatorisk

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Traumatic avulsion fracture of the lesser trochanter in a dog.

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A 15-month-old 25 kg female spayed American Staffordshire Terrier was examined to determine the cause of a six month period of lameness of the left pelvic limb. Signs of severe pain were evident on hyperextension and simultaneous internal rotation or abduction of the left hip joint; crepitus or

Lesser saphenous vein thrombophlebitis: its natural history and implications for management.

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Little attention has been given to superficial thrombophlebitis and particularly to lesser saphenous vein thrombophlebitis (LSVT) by vascular surgeons. A prospective nonrandomized study was conducted to assess LSVT's potential association with deep venous thrombosis (DVT) as well as its natural

Sulfasalazine in dermatology: A lesser explored drug with broad therapeutic potential

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Sulfasalazine is an aminosalicylate primarily used in the treatment of rheumatoid arthritis and ulcerative colitis. Its immunomodulatory, anti-inflammatory, and antiproliferative properties make it a potential therapeutic option for various dermatological disorders. Owing to its wide range of

[Non-steroidal anti-inflammatory agents (NSAID's) with lesser side effects by selective inhibition of cyclo-oxygenase-2].

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The efficacy and the adverse effects of non-steroid anti-inflammatory drugs (NSAIDs) are related mostly to inhibition of cyclo-oxygenase (COX), the main enzyme in prostaglandin synthesis. There are two isoenzymes: COX-1, mostly involved in the production of prostaglandins that are important for the

[New non-steroidal anti-inflammatory drugs (NSAID's) with lesser side effects, and over-the-counter low-dose preparations].

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Three recent developments with respect to therapy with nonsteroidal anti-inflammatory drugs (NSAIDs) are the identification of two isoenzymes of cyclooxygenase (COX-1 and COX-2), the development of NO-NSAIDs, and the availability of low-dose over-the-counter (OTC) NSAIDs. COX-1 products mainly have

[Subligamentous transfer of the extensor digitorum brevis tendon for medial malalignment of the lesser toes].

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OBJECTIVE Realignment of medially deviated lesser toes II-IV via subligamentous transfer of the extensor digitorum brevis tendon to treat painful toe disorders. METHODS Flexible medial malalignment of the lesser toes II-IV attributed to transverse instability of the metatarsophalangeal

CLINICAL MANAGEMENT OF THIRD PHALANX FRACTURES IN LESSER (TRAGELAPHUS IMBERBIS) AND GREATER KUDU (TRAGELAPHUS STREPSICEROS).

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Two greater kudu ( Tragelaphus strepsiceros ) and one lesser kudu ( T. imberbis ) from two zoological institutions presented with overgrown front hooves, and were diagnosed with fractures of the third phalanges in the affected digits. Both greater kudu had milder lamenesses at diagnosis, and were

Robust pro-inflammatory and lesser anti-inflammatory immune responses during primary simian varicella virus infection and reactivation in rhesus macaques.

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Simian varicella virus (SVV) infection of non-human primates models human varicella zoster virus (VZV) infection. Assessment of cell signaling immune responses in monkeys after primary SVV infection, after immunosuppression and during reactivation revealed strong pro-inflammatory responses and

Adiponectin correlates with body mass index and to a lesser extent with left ventricular mass in dialysis patients.

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BACKGROUND Adiponectin is a serum protein produced by adipose tissue which exerts anti-inflammatory, anti-diabetic and anti-atherosclerotic properties, hence is considered a cardio-protective marker. With the current uncertain role of adiponectin in dialysis patients to the aim of this study was to

Apoptosis induction in gastric mucous cells in vitro: lesser potency of Helicobacter pylori than Escherichia coli lipopolysaccharide, but positive interaction with ibuprofen.

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Non-steroidal anti-inflammatory drugs (NSAIDs) cause peptic ulcer disease, but whether they interact with Helicobacter pylori to promote damage is controversial. Moreover, the reported induction of apoptosis in gastric cells by H. pylori lipopolysaccharide (LPS) (10(-9) g/ml) contrasts with studies

A diarylheptanoid from lesser galangal (Alpinia officinarum) inhibits proinflammatory mediators via inhibition of mitogen-activated protein kinase, p44/42, and transcription factor nuclear factor-kappa B.

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The diarylheptanoid 7-(4'-hydroxy-3'-methoxyphenyl)-1-phenylhept-4-en-3-one (HMP) is a naturally occurring phytochemical found in lesser galangal (Alpinia officinarum). In the present study, we have demonstrated the anti-inflammatory properties of this compound on mouse macrophage cell line (RAW

Effect of anti-inflammatory drugs on lipase in vitro.

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Mefenamic acid, and to a lesser extent, flufenamic acid have a significant inhibitory effect on lipolysis as determined by the action of mouse pancreas lipase on the dilauric (didodecanoic) acid ester of fluorescein. Ibuprofen, fenoprofen calcium, phenylbutazone, oxyphenbutazone and alclofenac had

Synthesis and antioxidant, anti-inflammatory and gastroprotector activities of anethole and related compounds.

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Some derivatives of trans-anethole [1-methoxy-4-(1-propenyl)-benzene] (1) were synthesized, by introducing hydroxyl groups in the double bond of the propenyl moiety. Two types of reactions were performed: (i) oxymercuration/demercuration that formed two products, the mono-hydroxyl derivative,

The influence of some non-steroidal anti-inflammatory drugs on the retraction of collagen lattices.

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The effects of some antirheumatics on the formation and retraction of collagen lattices seeded with fibroblasts have been studied. Among the antirheumatics, diclofenac was the most active inhibitor of lattice retraction, then tropesin and to a lesser extent indomethacin. Ibuprofen which is known as

Microwave assisted one pot synthesis of some pyrazole derivatives as a safer anti-inflammatory and analgesic agents.

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A series of pyrazolo[3,4-b]quinolines have been synthesized using one-pot water mediated synthetic route under microwave irradiation involving the condensation of 2-chloroquinoline-3-carbaldehydes with semicarbazide or 2,4-dinitrophenyl hydrazine. The compounds were evaluated for their

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