nordentatin/clausena excavata

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[Chemical constituents from stems of Clausena excavata].

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OBJECTIVE To study the chemical constituents from the stems of Clausena excavata. METHODS The constituents were isolated by various chromatographic techniques(silica gel, RP-MPLC and PHPLC) and their structures were determined on the basis of their spectroscopic data, as well as

A new pyrano coumarin from Clausena excavata roots displaying dual inhibition against α-glucosidase and free radical.

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A new pyrano coumarin, identified as excavatin A (1) together with two known compounds nordentatin (2) and binorpocitrin (3) was isolated from the 95% EtOH extract of Clausena excavata. All structures were elucidated by using spectroscopy methods such as extensive NMR and HR-FAB-MS spectrometry. All

Carbazole-pyranocoumarin conjugate and two carbazole alkaloids from the stems of Clausena excavata.

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A carbazole-pyranocoumarin conjugate, carbazomarin B (1), and two carbazole alkaloids, 6-methoxymukonidine (2) and 2-hydroxy-3-methoxycarbazole (3), together with 27 known compounds (4-30), were isolated from the stems of Clausena excavata. Their structures have been elucidated by spectroscopic

Anti-HBV and cytotoxic activities of pyranocoumarin derivatives.

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Four natural pyranocoumarins clausenidin (1), nordentatin (2), clausarin (3), and xanthoxyletin (4) were isolated from the medicinal plant Clausena excavata. Recently, we found that 1 and 2 suppressed hepatitis B virus surface antigen in HepA2 cells, and in addition, 1-3 showed cytotoxic activity

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