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Polymicrogyria in a fetus with human parvovirus B19 infection: a case with radiologic-pathologic correlation.

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We report the prenatal magnetic resonance imaging (MRI) appearance of polymicrogyria with pathologic correlation in a fetus with congenital parvovirus B19 infection. Prenatal ultrasound revealed non-immune hydrops, but detected no fetal brain abnormalities. A subsequent fetal MRI scan performed at

Polymicrogyria and congenital parvovirus b19 infection.

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Fetal parvovirus B19 infection causes anemia, hydrops, and pregnancy loss but is generally not considered teratogenic. Nevertheless, disturbances of neuronal migration have been described with congenital parvovirus infection. We evaluated a term infant with congenital parvovirus disease and

[Diagnostic imaging of the CNS disorders].

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In this lecture, I attempted to demonstrate MR imaging of the cerebral tracts, medullospinal junction and spinal cord. Cortical migration disorders includes heterotopic gray matter, pachygyria and polymicrogyria. Delayed myelination and dysmyelination are shown as hyper signal intensity in the white

Disturbance of cerebral neuronal migration following congenital parvovirus B19 infection.

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OBJECTIVE We describe the clinical course of an infant who presented with severe fetal anemia and fetal hydrops following congenital parvovirus B19 infection before 16 gestational weeks. The fetus was treated by cordocentesis and intrauterine transfusion at 18 weeks. RESULTS The infant demonstrated

White matter spongiosis with vigabatrin therapy for infantile spasms.

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The histopathology, "white matter spongiosis," defined by electron microscopy (EM) as "intramyelinic edema," has been associated with vigabatrin therapy in various animal models, but its role or significance in clinical studies is unknown. We conducted a neuropathological examination on a

Mechanics of the brain: perspectives, challenges, and opportunities.

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The human brain is the continuous subject of extensive investigation aimed at understanding its behavior and function. Despite a clear evidence that mechanical factors play an important role in regulating brain activity, current research efforts focus mainly on the biochemical or

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