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Low level lead exposure during lactation increases rough and tumble play fighting of juvenile rats.

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Lactating rats were given distilled water or distilled water containing 0.067% lead chloride (500 ppm lead) as their sole source of drinking fluid from Days 1-21 of lactation. Activity, social investigation and rough and tumble play fighting behaviors of the offspring were observed on Day 26 and

The effects of transdermal scopolamine on simulated ship navigation and attention/reaction time.

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Transdermal scopolamine is commonly used by mariners to prevent or treat seasickness. Most studies indicate that scopolamine administered transdermally via an adhesive patch does not impair performance of skills required to navigate a vessel, but trials have not been conducted testing navigation and

The Republic of Singapore Navy's Scopoderm TTS study: results after 2,200 man-days at sea.

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Most clinical trials investigating prevention of seasickness with transdermal scopolamine have been short-term, and little information regarding long-term use is available. We report here a double-blind trial conducted on board a flat-bottomed Republic of Singapore Navy vessel of 2,490 tons, sailing

Play soliciting in juvenile male rats: effects of caffeine, amphetamine and methylphenidate.

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Three standard CNS stimulants were tested for effect on juvenile play soliciting in prepubertal male rats (n = 120). Three dosages of each stimulant were compared with a saline control. Soliciting behavior was isolated and magnified by a novel method incorporating pretest social deprivation and

What the ancient Greeks and Romans knew (and did not know) about seasickness.

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OBJECTIVE To find and analyze descriptions in ancient Greek and Roman literature that reveal what was known at the time about seasickness. METHODS A systematic search was made in the original literature beginning in the Greek period with Homer in ca 800 bc and extending up to Aetios Amidenos in the

Place conditioning reveals the rewarding aspect of social interaction in juvenile rats.

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Rewards, as diverse as food, sweetened solutions, copulation, electrical brain stimulation, and drugs abused by humans, have been shown to condition place preferences in rats. Juvenile rats will readily learn to traverse a T-maze for the opportunity to interact with another similar-aged rat. This

Testing social acoustic memory in rats: effects of stimulus configuration and long-term memory on the induction of social approach behavior by appetitive 50-kHz ultrasonic vocalizations.

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Rats emit distinct types of ultrasonic vocalizations (USVs), which serve as situation-dependent affective signals. In appetitive situations, such as rough-and-tumble-play, high-frequency 50-kHz USVs occur, whereas low-frequency 22-kHz USVs can be observed in aversive situations, such as social

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