Thunbergia laurifolia Linn. (TH) and Simplocos racemosa Roxb. (SY) are herbal medicines used in the treatment of drug addiction without scientific support for their mechanism of action. The present study investigated the effects of these medicinal plants on dopaminergic neurotransmission in
BACKGROUND
Thunbergia laurifolia Linn. (TL) is a herbal medicine used as an antidote for several poisonous agents in Thai traditional medicine. TL were reported not only to significantly increase potassium-stimulated dopamine release from rat striatal slices but also potentiated the effect of
BACKGROUND
Thunbergia laurifolia Linn. (TL) is an herbal medicine used to treat alcohol and drug addiction in Thai traditional medicine. A previous study demonstrated that an extract of TL increases rat striatal dopamine release in vitro.
OBJECTIVE
This study determined whether a methanol extract of
BACKGROUND
Thunbergia laurifolia Linn. (TL) is a herbal medicine which has been used as a component of a mixture ofcrude extracts to treat drug addicted patients. TL extract was reported to increase dopamine levels significantly in the rat brain both in vitro and in vivo studies similar to that seen
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