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adrenocortical hyperfunction/albumin

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Ratio of urinary protein to creatinine and albumin to creatinine in dogs with diabetes mellitus and hyperadrenocorticism.

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Long-term follow-up of renal function in dogs after treatment for ACTH-dependent hyperadrenocorticism.

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BACKGROUND Systemic hypertension and proteinuria are frequent complications in dogs with Cushing's syndrome and do not always resolve after treatment of hypercortisolism. Therefore, dogs with Cushing's syndrome may be at risk for renal dysfunction before and after treatment. OBJECTIVE To assess

Frequency of pulmonary mineralization and hypoxemia in 21 dogs with pituitary-dependent hyperadrenocorticism.

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The purpose of this study was to determine the frequency of hypoxemia and pulmonary mineralization using 99mTc-methylene diphosphonate (99mTc-MDP) in dogs with pituitary-dependent hyperadrenocorticism (PDH). Twenty-one dogs with PDH were prospectively evaluated using thoracic radiography, arterial

Hyperparathyroidism in dogs with hyperadrenocorticism.

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OBJECTIVE To assess the effect of canine hyperadrenocorticism (HAC) on parathyroid hormone (PTH), phosphate and calcium concentrations. METHODS PTH concentrations and routine biochemical parameters were measured in 68 dogs with HAC. Ionised calcium was measured in 28 of these dogs. The results

Validation of a simple method of estimating plasma free cortisol: role of cortisol binding to albumin.

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OBJECTIVE To develop, optimize, and validate a generalized mass action, equilibrium solution that incorporates measured concentrations of albumin as well as cortisol binding globulin (CBG) to estimate free cortisol. METHODS Free cortisol was estimated by Coolens method or by cubic equilibrium

Serum albumin as a determinant of cortisol release in patients with acute ischemic stroke.

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OBJECTIVE Animal studies demonstrated that protein malnutrition increases pituitary-adrenorcortical activity and leads to excessive cortisol release. The aim of our study was to determine the association between serum albumin and cortisol level in patients with acute ischemic

Hyperadrenocorticism in a ferret.

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A 7-year-old adult male ferret had progressive hair loss that was bilaterally symmetric. Also clinically evident were severe dehydration, polydipsia, muffled heart sounds, weak femoral pulses, hepatomegaly, lethargy, weakness, temporal muscular atrophy, dyspnea, and weakness. The blood profile of
BACKGROUND Acute phase proteins (APPs) are promising markers of inflammation in dogs, because they are more sensitive than WBC counts in detecting clinical and subclinical inflammation. Endogenous corticosteroids can mask an acute phase response and make it more difficult to identify underlying

HYPERTHYROXINEMIA AND HYPERCORTISOLEMIA DUE TO FAMILIAL DYSALBUMINEMIA

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A 23 year old man and his grandmother with hyperthyroxinemia and hypercortisolemia were heterozygous for an ALB mutation (p. Arg218Pro), known to cause Familial Dysalbuminemic Hyperthyroxinemia (FDH). However, serum free cortisol levels in these individuals were normal and total cortisol

Hypercortisolism affects glomerular and tubular function in dogs.

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Renal function was assessed in 25 dogs with Cushing's syndrome and in 12 healthy controls. Routine renal parameters and glomerular filtration rate (GFR) were measured and urinary biomarkers such as urinary albumin (uALB), urinary immunoglobulin G (uIgG), and urinary retinol-binding protein (uRBP)

[Changes in levels of acute phase proteins in patients with central hypercortisolism].

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BACKGROUND Acute phase protein reaction depends on complex interaction of proinflammatory cytokines and hormones, especially glucocorticoids. Glucocorticoids are essential factors for hepatocellular microenvironment and proteosynthesis during both rest and inflammatory period. Cushing's disease

The effects of hydrocortisone on systemic arterial blood pressure and urinary protein excretion in dogs.

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BACKGROUND Hypertension and proteinuria are commonly recognized in dogs with spontaneous hypercortisolism. There is, however, little information regarding the effect of exogenous glucocorticoids on blood pressure (BP) and proteinuria and whether these changes are reversible. OBJECTIVE Hydrocortisone

Plasma insulin, growth hormone, cortisol, and central obesity among young Chinese type 2 diabetic patients.

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OBJECTIVE To examine the relationships between central obesity, insulin resistance index, plasma insulin, growth hormone (GH), and cortisol concentrations in 90 young Chinese type 2 diabetic patients (aged 33+/-5 years) and 104 age- and sex-matched control subjects (aged 32+/-9 years). METHODS Young

Septic shock and sepsis: a comparison of total and free plasma cortisol levels.

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BACKGROUND Severe systemic infection leads to hypercortisolism. Reduced cortisol binding proteins may accentuate the free cortisol elevations seen in systemic infection. Recently, low total cortisol increments after tetracosactrin have been associated with increased mortality and hemodynamic
Depression, aging and female gender are associated with increased diurnal concentrations of total plasma cortisol. For the physical effects of hypercortisolemia, however, it is generally assumed that free rather than total plasma cortisol concentrations are of importance. Herein, we report a
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