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antidepressants/unwohlsein und ermüdung
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Protective effects of antidepressants against chronic fatigue syndrome-induced behavioral changes and biochemical alterations.
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Chronic fatigue syndrome (CFS) is characterized by profound fatigue, which substantially interferes with daily activities. The aim of this study was to explore the protective effects of antidepressants in an animal model of CFS in mice. Male albino mice were forced to swim individually for a period
Nitric oxide modulation in protective role of antidepressants against chronic fatigue syndrome in mice.
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OBJECTIVE
The present study was designed to elucidate the possible nitric oxide (NO) mechanism in the protective effect of antidepressants using mice model of chronic fatigue syndrome (CFS).
METHODS
Male albino laca mice were forced to swim for each 6 min session for 7 days and immobility period was
An investigation of the long-term benefits of antidepressant medication in the recovery of patients with chronic fatigue syndrome.
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Two hundred and seventy-five patients fulfilling the Centre for Disease Control (CDC) criteria for Chronic Fatigue Syndrome (CFS) completed measures assessing illness history, global ratings of well being, sleep, activity and psychopathology at baseline, 6 months, 18 months and 3 year follow-up.
Antidepressant therapy in the chronic fatigue syndrome.
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The chronic fatigue syndrome is a condition receiving increasing recognition. Symptoms of depression are not infrequent and may be persistent and severe enough to warrant treatment. The controversy over the use of antidepressant therapy in this condition may present a dilemma for the general
Excessive daytime sleepiness and fatigue in depressed patients and therapeutic response of a sedating antidepressant.
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BACKGROUND
Although sleepiness and fatigue are common symptoms in depressed patients, the relationships among sleepiness, fatigue and treatment of depression have not been fully elucidated. The main objective of this study was to investigate the therapeutic effects of a sedating antidepressant on
Symptoms of fatigue and cognitive/executive dysfunction in major depressive disorder before and after antidepressant treatment.
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Patients with major depressive disorder commonly experience fatigue and cognitive/executive dysfunction. These problems may be symptoms of the depression and persist despite effective antidepressant treatment, or these problems may emerge as adverse effects of some antidepressant treatments. A
Pharmacological treatment of chronic fatigue syndrome: focusing on the role of antidepressants.
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Chronic fatigue syndrome (CFS) is characterized by chronic, medically unexplained fatigue associated with effort- and stress-intolerance, widespread pain, and impairment in sleep and concentration. Although this constellation of symptoms is highly prevalent in clinical practice, the
Chronic fatigue syndrome: is there a role for non-antidepressant pharmacotherapy?
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BACKGROUND
Chronic fatigue syndrome (CFS) is a prevalent but poorly understood condition mainly characterized by debilitating, persistent or recurrent fatigue; increased physical and mental fatigability; cognitive impairment and widespread musculoskeletal pain. Despite intensive treatment research,
The effects of traditional tonics on fatigue in mice differ from those of the antidepressant imipramine: a pharmacological and behavioral study.
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The present studies were undertaken to investigate the differences between the antidepressant drug, imipramine, and liquid nutritive and tonic drugs (NTDs) that consist of Ginseng radix, Epimedii herba, Holen and an additional eight to twelve crude drugs. After preloading forced swimming, the NTD
Modafinil augmentation for residual symptoms of fatigue in patients with a partial response to antidepressants.
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OBJECTIVE
To evaluate the literature discussing the use of modafinil in the treatment of residual symptoms of fatigue in patients with depression.
METHODS
PubMed (1966-March 2007) and International Pharmaceutical Abstracts (1970-March 2007) were searched using the key words modafinil and depression.
Chronic fatigue syndrome, mast cells, and tricyclic antidepressants.
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Comments on guest editorial, "Chronic fatigue syndrome, mast cells, and tricyclic antidepressants".
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The chronic fatigue syndrome.
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The chronic fatigue syndrome (CFS) was formally defined in 1988 to describe disabling fatigue of at least 6 months' duration of uncertain etiology. Reports of CFS have emerged from the United States, Canada, the United Kingdom, Australia, New Zealand, Israel, Spain, and France. The disease primarily
Depression, fatigue, and functional disability in patients with chronic hepatitis C.
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OBJECTIVE
To examine the extent to which fatigue and functional disability correlate with severity of depressive symptoms in patients with chronic hepatitis C.
METHODS
Fifty patients with chronic hepatitis C were evaluated using structured psychiatric interviews and standardized rating
Establishing moderators and biosignatures of antidepressant response in clinical care (EMBARC): Rationale and design.
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Remission rates for Major Depressive Disorder (MDD) are low and unpredictable for any given antidepressant. No biological or clinical marker has demonstrated sufficient ability to match individuals to efficacious treatment. Biosignatures developed from the systematic exploration of multiple
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