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Seite 1 von 678 Ergebnisse
Occupational asthma caused by inhalation of bovine serum albumin powder.
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Bovine serum albumin (BSA), which is present in bovine plasma, is one of the major allergens affecting patients with food allergies induced by milk and meat. It is also commonly used in research laboratories. Although some reports have documented food allergies associated with BSA, BSA-induced
Longitudinal study of specific antibodies to toluene diisocyanate (TDI)-human serum albumin (HSA) conjugate in patients with TDI-induced asthma.
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BACKGROUND
An appreciable number of patients with toluene diisocyanate (TDI)-induced asthma have high serum levels of specific IgE (sIgE) antibody to TDI-human serum albumin conjugate (HSA). A recent investigation suggested a role of specific IgG (sIgG) in the development of TDI asthma.
METHODS
We
Specific immunoglobulin E and immunoglobulin G antibodies to toluene diisocyanate-human serum albumin conjugate: useful markers for predicting long-term prognosis in toluene diisocyanate-induced asthma.
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BACKGROUND
Our previous study reported that more than 50% of toluene diisocyanate (TDI)-induced asthma patients had persistent asthmatic symptoms even after complete avoidance. Although specific IgE (sIgE) has been detected in a portion of patients with TDI-asthma, a recent investigation suggests
Occupational asthma from nickel sensitivity: I. Human serum albumin in the antigenic determinant.
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Occupational asthma from nickel sensitivity was confirmed in a male worker (SB) by allergy skin tests and inhalational challenge. In an ammonium sulphate coprecipitation test 63Ni was selectively precipitated from SB plasma indicating antibody with nickel related specificity. Preincubation of 63Ni
Preliminary studies on the effect of rebamipide against the trypsin and egg-albumin induced experimental model of asthma.
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The present investigation was carried out to study the effect of rebamipide in experimentally induced bronchial asthma in mice. Trypsin and egg-albumin induced chronic model of asthma was used and various parameters were measured on the 35th day. The asthmatic control group showed lower level of
Ischemia-modified albumin levels in children with asthma: a pilot study.
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BACKGROUND
Hypoxia may occur in the severe exacerbations of asthma. Ischemia-modified albumin (IMA) may increase in ischemia, in addition to oxidative stress and inflammation. The aim was to evaluate IMA levels in children during the asthma exacerbation and the asymptomatic period.
METHODS
Children
Effects of corticosteroid inhalation therapy on the deposition pattern of Tc-99m human serum albumin radioaerosols in asthma.
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This study evaluated the effects of steroid inhalation on the deposition pattern of Tc-99m human serum albumin (Tc-99m HSA) radioaerosols in 25 asthma patients. A total of 12 normal controls also underwent the same examination. The pattern of radioaerosol deposition was quantitatively evaluated as
Cytokine secretion patterns of T cells responding to haptenized-human serum albumin in toluene diisocyanate (TDI)-induced asthma patients.
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Our understanding immune response mechanisms to chemical allergens has been limited. It was partly due to the nature of antigens, recognized by T cells, not being well characterized. In the present study, we examined a hypothesis that a reactive chemical allergen, toluene diisocyanate (TDI), react
Diverse profiles of specific IgE response to toluene diisocyanate (TDI)-human serum albumin conjugate in TDI-induced asthma patients.
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The prevalence studies on specific IgE to toluene diisocyanate (TDI)-human serum albumin (HSA) conjugate in TDI-induced asthma have shown variable results. In this study, we attempted to compare specific IgE bindings to TDI-HSA conjugate and its specificity using 3 different conjugates. Sera were
Technetium Tc 99m macroaggregated albumin lung scans. Use in chronic childhood asthma.
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Serial roentgenograms and technetium Tc 99m macroaggregated albumin lung scans were done simultaneously in 30 bronchodilator-dependent asthmatic children and young adults during both relative remission and attacks of status asthmaticus. When chest roentgenograms showed air trapping and increased
Occupational asthma and rhinoconjunctivitis from inhalation of crystalline bovine serum albumin powder.
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A 24-year-old white female laboratory technician developed recurrent rhinoconjunctivitis and wheezing immediately following repeated exposure to purified lyophilized bovine serum albumin (BSA). Prick and titrated intradermal skin tests revealed strongly positive results in the patient and negative
T-lymphocyte responses to plicatic acid-human serum albumin conjugate in occupational asthma caused by western red cedar.
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BACKGROUND
T cells are known to play a major role in the pathogenesis of atopic allergic asthma, but it is less clear whether they are involved in occupational asthma caused by low molecular weight chemicals such as plicatic acid.
OBJECTIVE
We sought to determine whether peripheral blood T cells
Investigating the role of altered systemic albumin concentration on the disposition of theophylline in adult and pediatric asthma patients by using the physiologically based pharmacokinetic approach.
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Theophylline is commonly used for the treatment of asthma and has a low hepatic clearance. The changes in plasma albumin concentration occurring in asthma may affect the exposure of theophylline. The aim of the presented work was to predict theophylline pharmacokinetics (PK) after incorporating the
Dietary Compound Kaempferol Inhibits Airway Thickening Induced by Allergic Reaction in a Bovine Serum Albumin-Induced Model of Asthma.
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Asthma is characterized by aberrant airways including epithelial thickening, goblet cell hyperplasia, and smooth muscle hypertrophy within the airway wall. The current study examined whether kaempferol inhibited mast cell degranulation and prostaglandin (PG) release leading to the development of
The change in the distribution of Tc-99m human serum albumin radioaerosols in asthma after a 1-week course of corticosteroid inhalation treatment.
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This study evaluated the effects of corticosteroid inhalation on the deposition pattern of Tc-99m HSA radioaerosols in 24 patients with asthma. The homogeneous degree of depositing radioaerosol was quantitatively evaluated using a modified standard score system over both lungs. The baseline scores
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