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13 Ergebnisse
Hesperidin and Diosmin for Treatment of COVID-19
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Research Background and Rationale At the end of December 2019, pneumonia of unknown origin was detected in the hospitals of Wuhan city, China, and reported to the WHO country office for the first time [1-3]. After a few days, the Chinese government has confirmed the human-to-human transmission of
Can Anti-asthmatic Medication Improve Sprint Performance in Healthy Endurance Athletes?
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Theoretical background:
The use of beta2-agonists in sports is restricted due to possible performance enhancing effects. The World Anti-Doping Agency's (WADA) prohibited list from January the 1st 2020 prohibits all use of beta2-agonists except inhaled salbutamol (maximum 1600 micrograms over 24
Roflumilast in Non-CF Bronchiectasis Study (2019)
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In a 4-week crossover study in 38 patients with COPD, roflumilast 500μg daily significantly reduced sputum absolute neutrophil count, IL-8 and neutrophil elastase compared with placebo treatment. Interestingly, the mechanism of anti-neutrophilic inflammation with roflumilast treatment in patients
Comparison of Ringer Lactate and Isotonic Acetate Solution as Perioperative Maintenance Fluid for Children
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Fluid therapy is aimed to compensate for fasting which is required for surgery, to meet the ongoing fluid losses and to maintain electrolyte balance during surgery. Fluid deficit of a healthy child who is not fed parenterally may be estimated by multiplying hourly maintenance requirement for fluid
Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation
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1.0 Background
While atrial fibrillation (AF) is the most common sustained cardiac arrhythmia requiring therapy, it is also associated with increased risk of stroke, heart failure, myocardial infarction, dementia, and death. The number of Americans affected with AF is expected to surge to nearly 16
Bortezomib in Late Antibody-mediated Kidney Transplant Rejection
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Background
Recent studies have underscored a dominant role of alloimmune injury as a leading cause of long-term graft loss in kidney transplantation. In this respect, the formation of antibodies against specific polymorphic donor antigens, commonly human leukocyte antigens (HLA), has turned out to
Banlangen Granules Anti-seasonal Influenza Study
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Inclusion criteria:
1. Patients have confirmed influenza A(H1N1,H3N2) or influenza B virus infection by real time PCR
2. age between 18-65 years old
3. axillary temperature ≥38ºC and with at least two constitutional symptoms (headache, chill, myalgia ，or fatigue) and one respiratory symptom (cough
An Open-Label Trial of Tocilizumab in Schizophrenia
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Schizophrenia is a chronic, debilitating disorder with life-long consequences on affected individuals and families. Schizophrenia is also associated with impaired cognition or thinking, which persists despite currently available treatments, and is an important determinant of quality of life and
An Investigation of the Association Between Helicobacter Pylori Infection and Abdominal Pain in Cystic Fibrosis Patients
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Abdominal pain and Cystic Fibrosis Cystic fibrosis is the most common lethal autosomal recessive disease among Caucasians. CF is caused by a single gene mutation on chromosome 7, which encodes for a membrane protein, the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR channel
Transplantation of Umbilical Cord Blood Following Chemotherapy for Blood Cancers
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The success of BMT as a curative option for patients with malignancies is frequently limited by the inability to identify an appropriate donor in time for transplantation.
Transplantations utilizing umbilical cord blood stem cells are increasingly successful. Data suggest that there are fewer and
The Effect of Montelukast in Patients With Chronic Cough and Bronchial Hyperreactivity
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Chronic cough is a frequent problem in general practice and one of the most common reasons for referral to a respiratory clinic. Prospective studies have shown that the vast majority of cases of chronic cough are due to one or more of three conditions: rhinitis/postnasal drip syndrome, asthma and
Effects of Aircraft Cabin Altitude on Passenger Comfort and Discomfort
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Altitude affects human health and well being through its effect on tissue oxygenation by altering the partial pressure of oxygen in the gas that enters the lungs. The partial pressure of any component of a mixed gas is equal to the total pressure of the gas multiplied by the fraction of the gas that
Proteomic Profiling for Influenza
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The central hypothesis of this study is that immune responses to vaccination can be quantified by proteomic profiling of serum (and other clinical fluids), and that the host responses to different infectious agents are unique and can be 'fingerprinted' by proteomics. Using influenza virus
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