13 Ergebnisse
BACKGROUND OF THE INVENTION
a. Field of Invention
This invention relates to tricyclic acetic acid derivatives, to their preparation and use, and to intermediates used for their preparation.
More specifically, this invention relates to tricyclic acetic acid derivatives in which the tricyclic portion
BACKGROUND OF THE INVENTION
1. Field of Invention
This invention relates to tricyclic acetic acid derivatives, to their preparation and use, and to intermediates used for their preparation.
More specifically, this invention relates to tricyclic acetic acid derivatives in which the tricyclic portion
BACKGROUND OF THE INVENTION
a. Field of Invention
This invention relates to tricyclic acetic acid derivatives, to their preparation and use, and to intermediates used for their preparation.
More specifically, this invention relates to tricyclic acetic acid derivatives in which the tricyclic portion
Disclosed herein are new carbazole compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of histamine receptor activity in a human or animal subject are also provided for the treatment diseases such as inflammation, asthma, rhinitis,
BACKGROUND OF THE INVENTION
This invention relates to novel tetrahydrocarbazole acetic acid derivatives possessing lipoxygenase inhibitory and/or cyclooxygenase inhibitory activity which are useful as anti-inflammatory and antiallergic agents. For instance, they exhibit analgesic and
BACKGROUND OF THE INVENTION
This invention relates to novel tetrahydrocarbazole acetic acid derivatives possessing lipoxygenase inhibitory and/or cyclooxygenase inhibitory activity which are useful as anti-inflammatory and antiallergic agents. For instance, they exhibit analgesic and
This application is a 317 of PCT/EP93/03611, filed Dec. 20,1993
BACKGROUND
Protein kinase C plays an important key role for intracellular signal transduction and is closely connected with the regulation of contractile, secretory, and proliferative processes. On the basis of these properties, the
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is the U.S. National Phase Application of PCT/US2009/059558, filed Oct. 5, 2009, which claims the benefit of U.S. Provisional Application Ser. No. 61/102,913, filed Oct. 6, 2008, each incorporated herein by reference in their entirety.
FIELD
FIELD OF THE INVENTION
This invention relates to carbazole compounds, to methods of preparing the compounds, to pharmaceutical compositions containing the compounds, and to their use as therapeutic agents. In particular, the invention relates to carbazole compounds and their use in a variety of
FIELD OF THE INVENTION
This invention relates to carbazole compounds, to methods of preparing the compounds, to pharmaceutical compositions containing the compounds, and to their use as therapeutic agents. In particular, the invention relates to carbazole compounds and their use in a variety of
FIELD OF THE INVENTION
This invention relates to carbazole compounds, to methods of preparing the compounds, to pharmaceutical compositions containing the compounds, and to their use as therapeutic agents. In particular, the invention relates to carbazole compounds and their use in a variety of
FIELD OF THE INVENTION
The present invention relates to the use of indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano [3,4-b]indole, 1,3,4,9-tetrahydrothiopyrano [3,4-b]indole, 1,2,3,4-tetrahydro-4H carbazole or 2,3,4,9-tetrahydro-1H-carbazole nucleus, such as etodolac, in the
BACKGROUND OF THE INVENTION
This invention relates to novel carbazoles. 5,6,7,8-Tetrahydrocarbazole-1-carboxylic acid and carbazole-1-carboxylic acid are known (J. chem. Soc., London, 1945, 530).
SUMMARY OF THE INVENTION
In a composition aspect, this invention relates to novel carbazoles of the