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carbazole/entzündung

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ArtikelKlinische VersuchePatente
13 Ergebnisse

2,3,4,9-tetrahydro-1H-carbazole acetic acid derivatives, composition and use as anti-inflammatories

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BACKGROUND OF THE INVENTION a. Field of Invention This invention relates to tricyclic acetic acid derivatives, to their preparation and use, and to intermediates used for their preparation. More specifically, this invention relates to tricyclic acetic acid derivatives in which the tricyclic portion

Preparation of 2,3,4,9-tetrahydro-1H-carbazole acetic acid derivatives

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BACKGROUND OF THE INVENTION 1. Field of Invention This invention relates to tricyclic acetic acid derivatives, to their preparation and use, and to intermediates used for their preparation. More specifically, this invention relates to tricyclic acetic acid derivatives in which the tricyclic portion

Substituted 2,3,4,9-tetrahydro-1H-carbazole-1-acetic acid derivatives, composition and use

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BACKGROUND OF THE INVENTION a. Field of Invention This invention relates to tricyclic acetic acid derivatives, to their preparation and use, and to intermediates used for their preparation. More specifically, this invention relates to tricyclic acetic acid derivatives in which the tricyclic portion

Carbazole inhibitors of histamine receptors for the treatment of disease

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Disclosed herein are new carbazole compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of histamine receptor activity in a human or animal subject are also provided for the treatment diseases such as inflammation, asthma, rhinitis,

Substituted 2,3,4,9-tetrahydro-1H-carbazole-1-acetic acid derivatives, composition and use

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BACKGROUND OF THE INVENTION This invention relates to novel tetrahydrocarbazole acetic acid derivatives possessing lipoxygenase inhibitory and/or cyclooxygenase inhibitory activity which are useful as anti-inflammatory and antiallergic agents. For instance, they exhibit analgesic and

Substituted 2,3,4,9-tetrahydro-1H-carbazole-1-acetic acid derivatives, composition and use

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BACKGROUND OF THE INVENTION This invention relates to novel tetrahydrocarbazole acetic acid derivatives possessing lipoxygenase inhibitory and/or cyclooxygenase inhibitory activity which are useful as anti-inflammatory and antiallergic agents. For instance, they exhibit analgesic and

Bis-indolyl maleinimide or indolopyrrolo carbazole containing an amino acid as PKC inhibitors

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This application is a 317 of PCT/EP93/03611, filed Dec. 20,1993 BACKGROUND Protein kinase C plays an important key role for intracellular signal transduction and is closely connected with the regulation of contractile, secretory, and proliferative processes. On the basis of these properties, the

Carbazole compounds and therapeutic uses of the compounds

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CROSS-REFERENCE TO RELATED APPLICATIONS This application is the U.S. National Phase Application of PCT/US2009/059558, filed Oct. 5, 2009, which claims the benefit of U.S. Provisional Application Ser. No. 61/102,913, filed Oct. 6, 2008, each incorporated herein by reference in their entirety. FIELD

Carbazole compounds and therapeutic uses of the compounds

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FIELD OF THE INVENTION This invention relates to carbazole compounds, to methods of preparing the compounds, to pharmaceutical compositions containing the compounds, and to their use as therapeutic agents. In particular, the invention relates to carbazole compounds and their use in a variety of

Carbazole compounds and therapeutic uses of the compounds

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FIELD OF THE INVENTION This invention relates to carbazole compounds, to methods of preparing the compounds, to pharmaceutical compositions containing the compounds, and to their use as therapeutic agents. In particular, the invention relates to carbazole compounds and their use in a variety of

Carbazole compounds and therapeutic uses of the compounds

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FIELD OF THE INVENTION This invention relates to carbazole compounds, to methods of preparing the compounds, to pharmaceutical compositions containing the compounds, and to their use as therapeutic agents. In particular, the invention relates to carbazole compounds and their use in a variety of

Methods and compositions for the treatment of chronic lymphocytic leukemia

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FIELD OF THE INVENTION The present invention relates to the use of indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano [3,4-b]indole, 1,3,4,9-tetrahydrothiopyrano [3,4-b]indole, 1,2,3,4-tetrahydro-4H carbazole or 2,3,4,9-tetrahydro-1H-carbazole nucleus, such as etodolac, in the

5,6,7,8:Tetrahydrocarbazole-1-carboxylic acid derivatives

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BACKGROUND OF THE INVENTION This invention relates to novel carbazoles. 5,6,7,8-Tetrahydrocarbazole-1-carboxylic acid and carbazole-1-carboxylic acid are known (J. chem. Soc., London, 1945, 530). SUMMARY OF THE INVENTION In a composition aspect, this invention relates to novel carbazoles of the
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