Patients followed within the Immuno-Allergology Service of the CHU Brugmann Hospital, who received an allergy assessment between 01/01/2015 and 31/12/2015. At least 1400 dermis will be analyzed. The allergens tested include: dermatophagoides pteronyssinus (DEPT), dermatophagoides farinae (DPF), blomia, cat, dog, cockroach, orchardgrass, timothy grass, alder, hazel,birch, olive tree, cypress, ash, latex, aspergillus, alternaria, cladosporium, peanut, hazel.

Allergy

The results of the allergen skin tests will be encoded as the edema diameter. The allergenicity score (mean of the skin reactivities for each allergen) will be compared between each age groups. The impact of tabagism, gender, BMI and residential area on the allergic reactivity will also be assessed in the overall population and within each age group.

Retrospective analysis of patient files

CHU Brugmann

Impact of Age on the Prevalence of Allergic Sensitization

Mean of the skin reactivities for each allergen. The results of the allergen skin tests are encoded as the edema diameter. Scores will be compared between the different age groups.

Effect of the smoking/non smoking status on the allergic reactivity, analysed in the hole group and in the different age groups.

Effect of the area of residence on the allergic reactivity, analysed in the hole group and in the different age groups.

Gender effect on the allergic reactivity, analysed in the hole group and in the different age groups.

Effect of the body mass index on the allergic reactivity, analysed in the hole group and in the different age groups.

Olivier Michel

Head of clinic

Brugmann University Hospital

Subjects will use dust mite Dermatophagoides pteronyssinus (Dp) extract or placebo nasal spray at home for 2 weeks, with a 1 month washout period followed by 2 weeks of the other nasal spray.

ALLERGIC RHINITIS

intervention will be to stop study drug or placebo

dust mite extract or placebo

Usf Asthma Allergy and Immunology Cru

Repeated Nasal Challenge in Skin Prick-puncture Negative and Intradermal Positive Dust Mite Allergic Rhinitis Patients

Repeated Nasal Challenge in Skin Prick-puncture Negative and Intradermal Positive Dust Mite Allergic Rhinitis Patients.

Mean increase in nasal lavage PGD2 and ECP by greater than 15 percent from baseline levels. Correlation between the orthogonol diameter of the wheal and flare of the intradermal skin test and the degree of symptom worse

cupressus/hochempfindlichkeit

Impact of Age on the Prevalence of Allergic Sensitization

Repeated Nasal Challenge in Skin Prick-puncture Negative and Intradermal Positive Dust Mite Allergic Rhinitis Patients

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