3 Ergebnisse
The ability of cannabinol and delta-8-tetrahydrocannabinol (delta-8-THC), two cannabinoid marihuana components, to modify delayed-type hypersensitivity (DTH) to sheep red blood cells (SRBC) was investigated in mice. Reduction of DTH reactivity by cannabinol required multiple, daily, postimmunization
The guinea pig maximization test was used to determine the potential of seven cannabinoids to produce allergic contact dermatitis. delta 9-Tetrahydrocannabinol and cannabinol were found to be extreme (Grade V) sensitizers. Cannabidiol, delta 8-tetrahydrocannabinol, and cannabichromene were moderate
delta 8-Tetrahydrocannabinol (THC)- and 8 beta, 9 beta-epoxyhexahydrocannabinol (EHHC)-tolerant mice were tolerant to the hypothermia produced by morphine while 8 alpha, 9 alpha-EHHC-tolerant mice were not. Morphine-tolerant mice acquired partial tolerance to the hypothermic effect of 8 alpha,9