Roux-en-Y Gastric Bypass

Cholecystitis; Gallstone

Gallbladder Diseases

Study Arm: robotic gastric bypass without cholecystectomy Control Arm: robotic gastric bypass with cholecystectomy

Robotic gastric bypass with or without cholecystectomy

Visceral Surgery, Department of Surgery, University Hospital Geneva

Randomized Trial Comparing Gastric Bypass With and Without Cholecystectomy

Pilot Open Randomized Controlled Trial Comparing Patients Undergoing Robotic Gastric Bypass With or Without Concomitant Cholecystectomy

Primary endpoint:
1. composite endpoint consisting of:
: intraoperative adverse events (common bile duct lesion, lesion of liver, lesion of digestive tract, bleeding, conversion).
: postoperative complications according to Dindo/Clavien Classification

- Common bile duct lesion
- Lesion of Liver
- Lesion of digestive tract
- bleeding
- conversion

2. Morbidity and mortality assessed by Dindo/ Clavien Classification system

length of hospital stay (discharge criteria defined as follows : absence of fever (T≤37.8), Neutrophils ≤12G/L, Absence of anemia, no nausea, no vomiting)

occurence of asymptomatic or symptomatic gallstones

cholecystitis, choledocholithiasis, cholangitis, biliary pancreatitis

Quality of life using the EQ-5D-5L questionnaire

Re intervention (Cholecystectomy, transgastric ERCP, biliary Revision)

Jung Minoa

Dr.med.

University of Geneva, Switzerland

Patients who meet the inclusion criteria will be randomized according to a randomization list generated by the CRC of the University Hospital of Geneva. The randomization envelops will be opened by the study staff at the appropriate time prior to the scheduling of gastric bypass after subject selection. The randomization assignment insert will contain information specifying whether the cholecystectomy will be performed or not during gastric bypass procedure.

Patients undergoing cholecystectomy for gall stones

Biliary Tract Cancer

Shanghai Cancer Institute

A Population-Based Case-Control Study of Biliary Tract Cancers in Shanghai, China

National Cancer Institute (NCI)

Chronic Pancreatitis

600microgm selenium, 0.54g vitamin C, 9000IU beta-carotene, 270IU vitamin E, 2g methionine per day, daily, in divided doses for 6 months

gallstones/− nicotin

Randomized Trial Comparing Gastric Bypass With and Without Cholecystectomy

A Population-Based Case-Control Study of Biliary Tract Cancers in Shanghai, China

Role of Antioxidants Supplementation in Chronic Pancreatitis

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