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hypoglycemia/epileptischer anfall
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Blood genomic responses differ after stroke, seizures, hypoglycemia, and hypoxia: blood genomic fingerprints of disease.
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Using microarray technology, we investigated whether the gene expression profile in white blood cells could be used as a fingerprint of different disease states. Adult rats were subjected to ischemic strokes, hemorrhagic strokes, sham surgeries, kainate-induced seizures, hypoxia, or insulin-induced
Independent and symmetric seizures from parasagittal cortex: is this a feature of profound hypoglycemia?
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Two patients presented with severe hypoglycemia and parasagittal homotopic cerebral hemisphere injury. Days after the initial insult, bilateral, independent, periodic lateralized epileptiform discharges and frequent seizures emerged from the affected homotopic cerebral cortices in both patients. We
Hypoglycaemia and seizures in large-for-gestational-age (LGA) full-term neonates.
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OBJECTIVE
To assess the risk of hypoglycaemia-associated seizures in large-for-gestational-age (LGA) full-term neonates data from the Netherlands Perinatal Registry were analysed.
RESULTS
From 1997 to 2002 hypoglycaemia was recorded in 1513 of 9318 (16.2%) admitted LGA (defined as birthweight > or =
Lactic acidosis and hypoglycemia: experimental evidence to show lactate prevents insulin induced seizures in rats.
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A 52-year-old man with lactic acidosis and severe hypoglycemia was fully conscious and alert with a blood sugar of 8 mgs%. We believe normal level of consciousness was maintained due to the presence of hyperlactatemia. We show experimental evidence to suggest that lactate prevents the development of
The hitchhiker's guide to the role of (transient) hypoglycemia in refractory seizures and epilepsy.
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Hypoglycemia and hypoglycorrhachia, although they are uncommon causes of refractory seizures and epilepsy, should always be considered because they are potentially treatable conditions. A high index of suspicion and low threshold for testing recurrent blood and at least one cerebrospinal fluid
Refractory Hypoglycemia and Seizures as the Initial Presenting Manifestation of Empty Sella Syndrome.
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An empty sella is reported to occur in 5.5%-23.5% of the population and is usually asymptomatic. It can be associated with endocrine disturbances. We report a 48-year-old woman who presented with refractory hypoglycemia, seizures, and shock that improved with levothyroxine, hydrocortisone, and
The Reversible Corpus Callosum Splenium Lesion in A Neonate with Hypoglycemia and Seizure.
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OBJECTIVE
Reversible splenial lesion syndrome is a distinct clinicoradiological syndrome with diverse etiologies. Hypoglycemia induced reversible splenial lesion syndrome has been documented in adults and children, but rare in neonates. We demonstrate a neonate with hypoglycemia presenting with a
Persistent hyperinsulinemic hypoglycaemia followed as benign infantile convulsion.
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An 18-month-old boy developed seizures at 3 months of age. He developed normally and, his EEG and brain CT revealed no abnormal findings. The blood sugar level was normal at that time, thus he was diagnosed as having benign infantile convulsion. At 7 months of age seizures reappeared, and
Effects of hypoglycemia on kindling seizures in suckling rats.
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The effects of insulin-induced hypoglycemia on epileptic disorders of suckling rats were examined using an amygdala kindling model. Kindling stimulations were conducted at 16 and 17 days of age with electrodes implanted in the amygdala 2 days earlier. In 18-day-old kindled rats, which acquired
Seizures and epilepsy in hypoglycaemia caused by inborn errors of metabolism.
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OBJECTIVE
The aim of the study was to characterize seizures and epilepsy related to hypoglycaemia.
METHODS
We analyzed the files of 170 consecutive patients referred for hypoglycaemia (onset 1h to 4y) caused by inborn errors of metabolism (glycogen storage disease type I, fatty acid β-oxidation
In vivo 31P and in vitro 1H nuclear magnetic resonance study of hypoglycemia during neonatal seizure.
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To examine the hypothesis that hypoglycemia has an adverse effect on brain energy state during seizure, neonatal dogs were subjected to bicuculline-induced seizure while hyperglycemic, normoglycemic, or hypoglycemic. Cerebral blood flow increased and remained elevated in all animals subjected to
Ondansetron-induced dystonia, hypoglycemia, and seizures in a child.
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OBJECTIVE
To document ondansetron-induced dystonia, hypoglycemia, and seizures in a child.
METHODS
A 4-year-old boy was admitted with dystonia following an intravenous dose of ondansetron 2 mg (0.13 mg/kg) that he had received for vomiting that day. In the emergency department, he developed
Severe hypoglycemia in a juvenile diabetic rat model: presence and severity of seizures are associated with mortality.
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It is well accepted that insulin-induced hypoglycemia can result in seizures. However, the effects of the seizures, as well as possible treatment strategies, have yet to be elucidated, particularly in juvenile or insulin-dependent diabetes mellitus (IDDM). Here we establish a model of diabetes in
Differential effects of low glucose concentrations on seizures and epileptiform activity in vivo and in vitro.
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In vivo, severe hypoglycemia is frequently associated with seizures. The hippocampus is a structure prone to develop seizures and seizure-induced damage. Patients with repeated hypoglycemic episodes have frequent memory problems, suggesting impaired hippocampal function. Here we studied the effects
Duration of nocturnal hypoglycemia before seizures.
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OBJECTIVE
Despite a high incidence of nocturnal hypoglycemia documented by the use of continuous glucose monitoring (CGM), there are no reports in the literature of nocturnal hypoglycemic seizures while a patient is wearing a CGM device.
METHODS
In this article, we describe four such cases and
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