optic neuritis/unwohlsein und ermüdung

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Efficacy of vision restoration therapy after optic neuritis (VISION study): study protocol for a randomized controlled trial.

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BACKGROUND Optic neuritis is a frequent manifestation of multiple sclerosis. Visual deficits range from a minor impairment of visual functions through to complete loss of vision. Although many patients recover almost completely, roughly 35% of patients remain visually impaired for years, and

[Disseminated choroiditis, papillitis and vasculitis retinae as main findings in lues II-III].

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Intraocular inflammations as chief manifestation of a T. pallidum infection associated with stage II syphilis are rarely documented in the recent literature. We report on a 35 year old patient with bilateral choroiditis, retinal vasculitis and papillitis persisting retrospectively since he had

Obstructive jaundice caused by Clonorchiasis-associated duodenal papillitis: a case report.

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We describe an unusual presentation of Clonorchis sinensis infection with obstructive jaundice due to duodenal papillitis which was relieved dramatically by endoscopic sphincterotomy. A 26-yr-old male presented with complaints of fatigue, weight loss and painless jaundice. The history was

Optic Neuritis Possibly Induced by Anti-PD-L1 Antibody Treatment in a Patient with Non-Small Cell Lung Carcinoma.

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UNASSIGNED Recent immune therapy with checkpoint inhibitors (CPIs) has demonstrated remarkable antitumor effects on specific tumors, such as malignant lymphoma and non-small cell lung carcinoma. By contrast, CPIs cause an imbalance in the immune system, triggering a wide range of immunological side

Optimal management of amiodarone therapy: efficacy and side effects.

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OBJECTIVE To review management and dosing guidelines for amiodarone therapy, and discuss the drug's adverse event profile. METHODS Review of relevant studies and reports. RESULTS Amiodarone is a highly effective antiarrhythmic drug, but is associated with adverse effects involving several organs.

[Pain in multiple sclerosis: prevalence, mechanisms, types and treatment].

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BACKGROUND Pain is a frequent symptom in multiple sclerosis (MS), although its prevalence and its importance vary from one study to another. OBJECTIVE To analyse the prevalence, types, mechanisms and treatments of the different painful syndromes that affect patients with MS. METHODS The work

Neurodegenerative Interplay of Cardiovascular Autonomic Dysregulation and the Retina in Early Multiple Sclerosis.

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Introduction: Autonomic nervous system (ANS) symptoms are prevalent in multiple sclerosis (MS) as is neurodegeneration. Our aim was to explore the occurrence of ANS symptoms and retinal neurodegeneration in a newly diagnosed MS population with tools available in a clinical setting.

Clinical trials in multiple sclerosis.

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In this past year, there has only been modest progress in the search for an effective treatment for multiple sclerosis and its complications, although a number of carefully designed trials are in progress. No treatment predictably slows the course of active disease. The marginal benefits previously

[Complications and diagnostic limitations of chronic meningitis].

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METHODS A 37-year-old woman was admitted with total loss of vision of the left eye within 24 hours. Additionally, she complained about fatigue, headache, chills, fever, muscle pain and neck stiffness since 4 days. At admission, the body temperature was 38.7 degrees C. Neurological examination

[Exploration of Mahuang Fuzi Xixin Decoction formula syndromes based on severe cases of critical care and its application for nosocomial infection in critical care medicine including hyperpyrexia after tracheotomy and severe pain accompanied by acute myocardial infarction and diabetic peripheral neuropathy].

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Mahuang Fuzi Xixin Decoction recorded in Treatise on Febrile Diseases by Zhang Zhongjing in the Han Dynasty have been widely used in treating Yang deficiency and exogenous wind-cold syndrome by traditional Chinese medicine physicians for thousands of years. The indications of Mahuang Fuzi Xixin

Large-scale digitoxin intoxication.

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Because of an error in the manufacture of digoxin tablets a large number of patients took tablets that contained 0.20 mg. of digitoxin and 0.05 mg. of digoxin instead of the prescribed 0.25 mg. of digoxin. The symptoms are described of 179 patients who took these tablets and suffered from digitalis

Multiple sclerosis: a primary care perspective.

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Multiple sclerosis (MS) is the most common permanently disabling disorder of the central nervous system in young adults. Relapsing remitting MS is the most common type, and typical symptoms include sensory disturbances, Lhermitte sign, motor weakness, optic neuritis, impaired coordination, and

Anti- IL-6 therapies for neuromyelitis optica spectrum disorders: A systematic review of safety and efficacy.

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Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune disease of the central nervous system that causes recurrent attacks of optic neuritis, myelitis, and brainstem symptoms, resulting in severe neurological disability. Preventive treatment with immunosuppressive

Adalimumab successful in sarcoidosis patients with refractory chronic non-infectious uveitis.

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BACKGROUND Adalimumab, a humanized monoclonal antibody targeted against TNF-α, has proved to be successful in the treatment of uveitis. Another anti-TNF-α agent, i.e., infliximab, has been reported of benefit in the treatment of refractory sarcoidosis. The aim of this prospective case series was to

Non-invasive visual evoked potentials to assess optic nerve involvement in the dark agouti rat model of experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein.

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Experimental autoimmune encephalomyelitis (EAE) is the primary disease model of multiple sclerosis (MS), one of the most diffused neurological diseases characterized by fatigue, muscle weakness, vision loss, anxiety and depression. EAE can be induced through injection of myelin peptides to

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