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1. Trade-offs between growth and immunity of nestling birds can be influenced by parasites, but the magnitude of these effects may depend on availability of critical dietary nutrients. Owing to their importance for both immune system function and growth, dietary carotenoids have the potential to
The kinetic release of lymphocyte activating factors by inflammatory rat polymorphonuclear leukocytes (PMNs) into culture fluid was studied. PMNs, collected from the pleural cavity of rats 4 hours after injection of either calcium pyrophosphate (CaPP) or normal plasma, released into the supernatant
In order to examine macrophages phagocytosing polymorphonuclear leucocytes (PMNs) in detail, we established a new method, whereby a large number of PMN-phagocytosing macrophages (PPMs) were easily induced. PPMs were harvested from the peritoneal cavity after thioglycollate medium, oyster glycogen,
Advocates of free distribution of marijuana and hashish describe these drugs as harmless. Several experimental in-vitro and in-vivo studies have shown the mutagenic and carcinogenic properties of tetrahydrocannabinol. Several carcinogenic polycyclic aromatic hydrocarbons have been extracted from tar
In the present study, we investigated the role of resident cells in the neutrophil migration induced by ovalbumin (OVA) in immunized rats. OVA administration induced dose-dependent neutrophil migration, which was inhibited by pretreating the animals with dexamethasone, but not with indomethacin or
HLA-DR antigens, the human equivalent of mouse I region-associated or Ia products, are polymorphic cell surface sialoglycoproteins involved in initiation of the immune response. Their expression is normally restricted to B lymphocytes, macrophages, dendritic and other antigen-presenting cells and
Carrageenan, a high molecular weight sulphated polygalactan, is a potent inhibitor of immune responses mediated by macrophages. In the present study, spleen cells from rats orally dosed with 5 mg/kg or 50 mg/kg Seakem 9 carrageenan displayed a long-lasting depression of T lymphocyte mitogenesis as
The influence of the respirable fraction of an iron ore dust on immunity has been studied. The iron ore dust enhanced the specific immune responses to both sheep erythrocytes and a bacterial lipopolysaccharide. The IgG class of antibody was enhanced significantly and its pattern of enhancement
A weakness of the hu-PBL-SCID model for the study of human immune functions is the appearance of anergy and the consequent loss of T cell function. We demonstrate here that human T cells retain normal functions during the early stage of chimerism. At 1 and 2 weeks post-engraftment, T cells isolated
Pregnancy inhibits macrophage accumulation within the peritoneal cavity of Wistar rats when inflammation is induced by phytohaemagglutinin (PHA). The inhibition of macrophages was considerably greater than that of polymorphonuclear leucocytes (PMNs) induced by sodium caseinate. Pregnancy did not
Lymphocyte proliferation stimulated with phytohaemagglutinin (PHA) was studied in vivo. For control aims experiments were done also lymphocytes without PHA. In the investigations the technique of diffusion chamber was used. Chambers with lymphocytes (1 X 10(6) cells in a chamber) were implanted into