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porphyrin/unwohlsein und ermüdung
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13 Ergebnisse
Fatigue syndromes revisited: the possible role of porphyrins.
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The author sees many patients with chronic oral problems of unknown etiology. It has been noticed that many of these patients also have complex medical histories. Fatigue and pain are two of the most common features observed. Some, but not all, also have other definitive medical diagnoses. Those
Dendronised Ni(ii) porphyrins as photoswitchable contrast agents for MRI.
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Light-responsive contrast agents for magnetic resonance imaging (MRI) based on Ni(ii) porphyrin molecular spin switches have recently been introduced. We present their implementation in water and methanol based gels leading to the first soft materials that are rewritable with light and readable with
An Unusual Cause of Headache and Fatigue in a Division 1 Collegiate Athlete.
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Variegate porphyria (VP) is an autosomal dominant disorder of porphyrin metabolism. We report a case of a 21-year-old male collegiate athlete who complained of recurrent headache and fatigue. Extensive testing after initial presentation failed to identify a cause. Months later, his grandmother was
The O2 cost of the tension-time integral in isolated single myocytes during fatigue.
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One proposed explanation for the Vo(2) slow component is that lower-threshold motor units may fatigue and develop little or no tension but continue to use O(2), thereby resulting in a dissociation of cellular respiration from force generation. The present study used intact isolated single myocytes
Lead poisoning due to hai ge fen. The porphyrin content of individual erythrocytes.
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A 45-year-old Korean man developed abdominal colic, muscle pain, and fatigue. Following a 3-week hospitalization, acute intermittent porphyria was diagnosed based on the symptoms and a high level of urinary delta-aminolevulinic acid (378 mumol/L [4.95 mg/dL]). However, discovery of an elevated blood
Light-controlled switching of the spin state of iron(III).
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Controlled switching of the spin state of transition metal ions, particularly of FeII and FeIII, is a prerequisite to achieve selectivity, efficiency, and catalysis in a number of metalloenzymes. Here we report on an iron(III) porphyrin with a photochromic axial ligand which, upon irradiation with
Porphyria: a new perspective.
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Recently, Medical Hypotheses has published two papers on fatigue syndromes and their relationship to porphyrin metabolism (1,2). This article continues the exploration of how many diseases may have abnormal porphyrin metabolism playing a role in their pathogenesis. Another issue is the need to
Haem arginate as effective maintenance therapy for hereditary coproporphyria.
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A 35-year-old woman presented with skin fragility and photosensitivity with blisters affecting her face and hands. Other symptoms included intermittent headache, fatigue, abdominal pain and nausea. Porphyrin studies were markedly raised, with features consistent with hereditary coproporphyria (HCP).
Lead and morbidity: A dose-response relationship.
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Many laboratory tests have been recommended for monitoring factory workers exposed to lead. To select the most useful test the best predictor of selected measures of morbidity was sought. 639 lead-exposed workers in several factories were questioned about abdominal ache, constipation, and fatigue
Phenazopyridine-induced sulfhemoglobinemia.
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OBJECTIVE
To report a case of sulfhemoglobinemia in a patient receiving phenazopyridine for a urinary tract infection.
METHODS
A 63-year-old white woman presented to the emergency department with complaints of fatigue and bluish discoloration of her body that had gradually progressed over the
Design and Synthesis of Photodissociable Ligands Based on Azoimidazoles for Light-Driven Coordination-Induced Spin State Switching in Homogeneous Solution.
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Light-switchable azoimidazoles were rationally designed and synthesized, and their performance was investigated as photodissociable ligands (PDL) and for spin state switching of Ni porphyrins. The rationally designed ligands exhibit a high photochemical conversion rate (trans → cis > 98%) and no
Profile of patients with chemical injury and sensitivity.
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Patients reporting sensitivity to multiple chemicals at levels usually tolerated by the healthy population were administered standardized questionnaires to evaluate their symptoms and the exposures that aggravated these symptoms. Many patients were referred for medical tests. It is thought that
Photoswitchable Magnetic Resonance Imaging Contrast by Improved Light-Driven Coordination-Induced Spin State Switch.
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We present a fully reversible and highly efficient on-off photoswitching of magnetic resonance imaging (MRI) contrast with green (500 nm) and violet-blue (435 nm) light. The contrast change is based on intramolecular light-driven coordination-induced spin state switch (LD-CISSS), performed with
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