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sorbic acid/hochempfindlichkeit
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Allergic and toxic reactions caused by cream bases in dermatological patients.
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Synopsis Irritant and allergic reactions from cream bases observed in eczema patients are reviewed. The frequency of allergic reactions to the ingredients of vehicles in eczema patients is an indication of allergic potential for normal skin. Against this background, hypoallergenic fragrances are
A novel role for the yeast protein kinase Dbf2p in vacuolar H+-ATPase function and sorbic acid stress tolerance.
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In Saccharomyces cerevisiae, the serine-threonine protein kinase activity of Dbf2p is required for tolerance to the weak organic acid sorbic acid. Here we show that Dbf2p is required for normal phosphorylation of the vacuolar H(+)-ATPase (V-ATPase) A and B subunits Vma1p and Vma2p. Loss of V-ATPase
Allergy to ingredients of vehicles.
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Common ingredients of vehicles such as perfumes, antibacterial agents, emulsifiers and other surface active agents, propylene glycol, lanolin and wool alcohols were tested in eczema patients over a three-year period. Perfume allergy was detected in 3.6% of the cases, sensitivity to thiomersal in 2%,
Toxicology of sorbic acid and sorbates.
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Sorbic acid and its salts have been subjected to an extensive battery of tests, including acute, short-term and chronic toxicity/carcinogenicity tests, two-generation reproduction and teratogenicity studies. These studies show that sorbic acid and sorbates have a very low level of mammalian
Hypersensitivity reactions to food additives.
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Only seldom have food additives been shown to cause true allergic (immunological) reactions. Adverse effects due to various pharmacological or other mechanisms are much more common. The individual tolerance may be decreased for one reason or another, and may fluctuate from time to time. Many
Weak Acid Resistance A (WarA), a Novel Transcription Factor Required for Regulation of Weak-Acid Resistance and Spore-Spore Heterogeneity in Aspergillus niger.
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Propionic, sorbic, and benzoic acids are organic weak acids that are widely used as food preservatives, where they play a critical role in preventing microbial growth. In this study, we uncovered new mechanisms of weak-acid resistance in molds. By screening a library of 401 transcription factor
[Results of studies in chronic urticaria with special reference to nutritional factors].
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In a clinical study 90 patients with chronic or chronic relapsing urticaria underwent a standardized diagnostic programme. In 61% of the cases no causing factors were to be found. In the remaining 39% the most common causes were represented by intolerance reactions (16%), infection causes (16%) and
[Contact sensitization in leg ulcers].
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BACKGROUND
The leading complication of leg ulcers is the development of peri-lesional eczema. The etiological diagnosis is often difficult due to the large number of topical agents used.
METHODS
Fifty patients, 35 women and 15 men, mean age 67.8 years, range 37-91 years, with leg ulcers of variable
Use of Sorbates in Meat Products, Fresh Poultry and Poultry Products: A Review 1.
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Extensive research conducted in recent years has examined the efficiency of both potassium sorbate and sorbic acid (sorbates) as antimicrobial agents in a wide range of processed meat, and fresh and processed poultry products. In addition to their action against pathogens, effects of sorbates on
Global phenotypic analysis and transcriptional profiling defines the weak acid stress response regulon in Saccharomyces cerevisiae.
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Weak organic acids such as sorbate are potent fungistatic agents used in food preservation, but their intracellular targets are poorly understood. We thus searched for potential target genes and signaling components in the yeast genome using contemporary genome-wide functional assays as well as DNA
Allergenic Ingredients in Facial Wet Wipes.
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BACKGROUND
Allergic contact dermatitis commonly occurs on the face. Facial cleansing wipes may be an underrecognized source of allergens.
OBJECTIVE
The aim of this study was to determine the frequency of potentially allergenic ingredients in facial wet wipes.
METHODS
Ingredient lists from name brand
[Contact sensitization to pharmaceutic aids in dermatologic cosmetic and external use preparations].
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From April 2001 to December 2002, a group of 514 patients (178 men, 336 women, average age 42.8 years) suffering from chronic eczema were tested by means of epicutaneous tests for contact hypersensitivity to selected auxiliary substances of dermatological external and cosmetic preparations. In 194
Immunoregulatory impact of food antioxidants.
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Immune system activation and inflammation are deeply involved in the pathogenesis of a variety of diseases including infections, autoimmunity and malignancy as well as allergy and asthma. The incidence of allergy and asthma has significantly increased during the past decades. Still the background of
Contact urticaria: Frequency, elicitors and cofactors in three cohorts (Information Network of Departments of Dermatology; Network of Anaphylaxis; and Department of Dermatology, University Hospital Erlangen, Germany).
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Allergenic Ingredients in Personal Hygiene Wet Wipes.
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BACKGROUND
Wet wipes are a significant allergen source for anogenital allergic contact dermatitis.
OBJECTIVE
The aim of the study was to calculate the frequency of potentially allergenic ingredients in personal hygiene wet wipes.
METHODS
Ingredient lists from brand name and generic personal hygiene
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