Planta Medica 1984-Feb
An approach to the antiinflammatory activity of borjatriol.
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The antiinflammatory activity of borjatriol (a diterpenoid isolated from SIDERITIS MUGRONENSIS Borja) was tested using the cotton pellet-granuloma assay. The compound inhibited the granuloma weight and the serum lysozyme activity in a dose-dependently way. The determination of this enzyme has allowed us to distinguish between an irritant (carrageenan) which reduces the granuloma weight and antiinflammatory substances (phenylbutazone and borjatriol).
