Bioorganic and Medicinal Chemistry Letters 2010-Mar
Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii.
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A new bisindole alkaloid, bisleuconothine A (1) consisting of an eburnane-aspidosperma type skeleton, was isolated from the bark of Leuconotis griffithii. The structure including absolute stereochemistry was elucidated on the basis of 2D NMR data and X-ray analysis. Bisleuconothine A (1) showed cell growth inhibitory activity against various human cancer cell lines.
