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antianginal/φλεγμονή
Ο σύνδεσμος αποθηκεύεται στο πρόχειρο
Σελίδα 1 από 51 Αποτελέσματα
Opioid pathways activation mediates the activity of nicorandil in experimental models of nociceptive and inflammatory pain.
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Σύνδεση εγγραφή
We have previously demonstrated that nicorandil inhibits the second phase of the nociceptive response induced by formaldehyde. In the present study, we evaluated the effects induced by nicorandil in other models of nociceptive and inflammatory pain in mice and also whether opioid pathways activation
[The influence of beta-adrenoblocking therapy on the markers of systemic inflammation in patients with acute coronary syndrome].
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Σύνδεση εγγραφή
The study was designed to estimate activity of a series of anti-inflammatory markers (C-reactive protein (CRP), ceruloplasmin, haptoglobulin, interleukin (IL)-4, and IL-8) in the acute phase of acute coronary syndrome (ACS) and effect of beta-adrenoblocking therapy on their activity. The patients
The anti-ischemic and anti-anginal properties of statins.
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Σύνδεση εγγραφή
Angina pectoris resulting from myocardial ischemia afflicts half of all patients with coronary heart disease (CHD). Chronic angina remains a major public health burden despite state-of-the-art therapies, and improvement in survival from myocardial infarction and CHD has only increased its
Obesity, inflammation and brachial artery flow-mediated dilatation: therapeutic targets in patients with microvascular angina (cardiac syndrome X).
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Σύνδεση εγγραφή
BACKGROUND
The pathophysiology of microvascular angina (cardiac syndrome X, CSX), (effort-induced angina, a positive response to exercise stress testing and angiographically normal coronary arteries) has not been fully elucidated. Various pathogenic mechanisms have been proposed, amongst which
Suppression of angioplasty-related inflammation by pre-procedural treatment with trimetazidine.
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Σύνδεση εγγραφή
Percutaneous transluminal coronary angioplasty (PTCA) has been recognized as a reliable treatment procedure for acute reversible ischemia and reperfusion. Ischemic reperfusion cycle in PTCA leads to the systemic inflammation and extensive tissue injury by the production of reactive oxygen species
Nicorandil alleviates ovalbumin-induced airway inflammation in a mouse model of asthma.
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Σύνδεση εγγραφή
Nicorandil is an antianginal drug that has anti-inflammatory property. This study aimed to investigate the effects of nicorandil on allergic asthma induced by ovalbumin (OVA) in mice in comparison with dexamethasone. Mice were sensitized to OVA (on days 0 and 7) and challenged with OVA three times
Trimetazidine protects against smoking-induced left ventricular remodeling via attenuating oxidative stress, apoptosis, and inflammation.
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Σύνδεση εγγραφή
Trimetazidine, a piperazine derivative used as an anti-anginal agent, improves myocardial glucose utilization through inhibition of fatty acid metabolism. The present study was designed to investigate whether trimetazidine has the protective effects against smoking-induced left ventricular
Nicorandil ameliorates pulmonary inflammation and fibrosis in a rat model of silicosis.
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Σύνδεση εγγραφή
Nicorandil, an antianginal and potassium channel opener agent, has different useful impacts on cardiovascular and respiratory systems. Its effect against silicosis has not been discussed yet, therefore, this is an attempt to decide whether nicorandil can reduce silica-induced lung injury in rats.
Effect of the anti-anginal agent, perhexiline, on neutrophil, valvular and vascular superoxide formation.
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Σύνδεση εγγραφή
The prophylactic anti-anginal agent, perhexiline, may also be effective in acute coronary syndromes and advanced aortic valvular stenosis, conditions associated with enhanced inflammation. Its potential effects on superoxide formation via NADPH oxidase were measured by lucigenin-mediated
Prevention of inflammation-mediated neurotoxicity by butylidenephthalide and its role in microglial activation.
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Σύνδεση εγγραφή
Microglial cells are the prime effectors in immune and inflammatory responses of the central nervous system (CNS). During pathological conditions, the activation of these cells helps restore CNS homeostasis. However, chronic microglial activation endangers neuronal survival through the release of
Inflammatory and neuropathic pain are rapidly suppressed by peripheral block of hyperpolarisation-activated cyclic nucleotide-gated ion channels.
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Σύνδεση εγγραφή
Previous studies have shown that hyperpolarisation-activated cyclic nucleotide-gated (HCN)-2 ion channels regulate the firing frequency of nociceptive sensory neurons and thus play a central role in both inflammatory and neuropathic pain conditions. Here we use ivabradine, a clinically approved
Early Effects of Treatment Low-Dose Atorvastatin on Markers of Insulin Resistance and Inflammation in Patients with Myocardial Infarction.
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Σύνδεση εγγραφή
Dyslipidemia is one of the primary causes of cardiovascular disease. Therefore, attention has been focused on the development of drugs that normalize lipid levels and exert an effect on markers of atherothrombosis, insulin resistance (IR), and inflammation. Atorvastatin is a drug with not only
Inflammatory arteritis with reversible coronary localization in a 70-year-old woman.
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Σύνδεση εγγραφή
Giant cell arteritis with coronary involvement is an uncommon event, often discovered at autopsy after a myocardial infarction. We report the case of a 70-year-old female with unstable angina pectoris persisting despite angioplasty and antianginal treatment, associated with chronically increased
[Anti-anginal medication in management of acute coronary syndrome].
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Σύνδεση εγγραφή
Pharmacological therapy for acute coronary syndrome (ACS) is divided into the treatment for myocardial ischemia and that for coronary thrombosis. Immediate nitrates(sublingual tablets and sprays) are used to alleviate attacks and patients not responding them are treated by intravenously in 24 hours.
Effects of Ranolazine on Astrocytes and Neurons in Primary Culture.
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Σύνδεση εγγραφή
Ranolazine (Rn) is an antianginal agent used for the treatment of chronic angina pectoris when angina is not adequately controlled by other drugs. Rn also acts in the central nervous system and it has been proposed for the treatment of pain and epileptic disorders. Under the hypothesis that
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