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Σελίδα 1 από 126 Αποτελέσματα
Dolichos biflorus agglutinin binding in hereditary bowel cancer.
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Σύνδεση εγγραφή
Dolichos biflorus agglutinin (DBA) binds specifically to N-acetylgalactosamine (GalNAc), one of the 5 sugars contributing to the oligosaccharide component of human colorectal goblet cell mucin. DBA binds to goblet cells of the upper crypt and surface epithelium within the proximal colon and to the
Dolichos biflorus agglutinin binding to intracranial germ-cell tumors: detection of embryonal components in germinomas.
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Σύνδεση εγγραφή
Dolichos biflorus agglutinin (DBA) binding was examined in 32 cases of intracranial human germ-cell tumors. In embryonal carcinomas, intense DBA binding sites were found on the free surface and cytoplasm of embryonal cells. In teratomas, glandular structures often had positive DBA binding sites.
Affinity of four lectins for endocervical and endometrial non-neoplastic and neoplastic glandular epithelium.
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Σύνδεση εγγραφή
OBJECTIVE
Endocervical and endometrial tissues were stained with four lectins to determine the difference in staining pattern between non-neoplastic and neoplastic conditions of these tissues.
RESULTS
The lectins used were Ulex europaeus agglutinin (UEA), Dolicho biflorus agglutinin (DBA).
Affinity cytochemistry of vascular endothelia in brain tumors by biotinylated Ulex europaeus type I lectin (UEA I).
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Σύνδεση εγγραφή
The vascularization of 50 tumors of the central nervous system (CNS) including 17 meningiomas, 25 neuroectodermal tumors, i.e., astrocytomas, oligodendrogliomas, mixed gliomas, glioblastomas, medulloblastomas, seven metastatic carcinomas, and one malignant hemangioendothelioma were investigated
Lectin staining of neoplastic and normal background colorectal mucosa in nonpolyposis and polyposis patients.
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Σύνδεση εγγραφή
A lectin histochemistry approach was adopted for comparative assessment of a colon cancer risk. Binding of Ulex europaeus agglutinin-I (UEA-I), peanut agglutinin (PNA), Griffonia simplicifolia agglutinin-II (GSA-II), and Dolichos biflorus agglutinin (DBA) was investigated in tumor and background
Comprehensive lectin histochemistry of normal and neoplastic human choroid plexus cells: alternation of lectin-binding patterns through neoplastic transformation.
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Σύνδεση εγγραφή
Lectin histochemistry of the normal and neoplastic human choroid plexus cells [six choroid plexus papillomas (CPPs) and three choroid plexus carcinomas (CPCs)] was performed using eight representative lectins to study the development of sugar chain structures and also to determine whether lectins
Regional differences in normal and cancer-associated glycoconjugates of the human colon.
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Σύνδεση εγγραφή
Because inherent regional differences in colonic epithelium may determine the biologic behavior of tumors originating from different sites, and inasmuch as colonic epithelial cells secrete mucins that may reflect the state of cell differentiation, colonic goblet cell mucin was analyzed with the use
Histochemically demonstrable changes in cell surface carbohydrates of human germ cell tumors.
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Σύνδεση εγγραφή
Cell surface carbohydrate chains of human germ cell tumors were investigated histochemically using peanut agglutinin (PNA), Dolichos biflorus agglutinin (DBA), Ulex europaeus agglutinin I (UEA-1), and anti-I-(Ma) antibody. Of 16 cases of embryonal carcinoma in adult testis, peanut agglutinin, a
Expression of N-acetyl galactosaminylated and sialylated glycans by metastases arising from primary breast cancer.
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Σύνδεση εγγραφή
This study examines the Helix pomatia lectin (HPA) binding characteristics of metastases arising from primary breast cancer, and compares HPA binding patterns with binding of Dolichos biflorus lectin (DBA), Limax flavus lectin (LFA), and a monoclonal antibody against the Tn epitope. Of 81 blocks of
Enhancement in accessibility to macrophages by modification of mucin-type carbohydrate chains on a tumor cell line: role of a C-type lectin of macrophages.
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Σύνδεση εγγραφή
We investigated the role of mucin-type (O-linked) carbohydrate chains of tumor target cells in the recognition by macrophages through a Gal/GalNAc-specific calcium-dependent lectin. Binding of a soluble form of this lectin to P815 mastocytoma cells was increased by treatment with benzyl-GalNAc,
Lectin staining of renal cell tumours with special emphasis on oncocytomas.
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Σύνδεση εγγραφή
There are conflicting results respecting the segmental tubular origin of renal oncocytomas, a type of tumour said to be highly differentiated and benign, though metastases have been described. The aim of this study was, by applying different lectins on renal cell carcinomas (n = 50) and oncocytomas
Binding of fluorescein isothiocyanate conjugated lectins to MXT mouse mammary neoplasm and their relation to steroid receptor status.
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Σύνδεση εγγραφή
As previous studies have suggested a hormone dependence of binding sites for peanut agglutinin in mammary neoplasm, this feature has been thought to be correlated to steroid receptor status. The present investigation was undertaken on a well-established ovarian-dependent cancer model in order to
Patchy field defects of apoptosis resistance and dedifferentiation in flat mucosa of colon resections from colon cancer patients.
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Σύνδεση εγγραφή
BACKGROUND
Abnormal areas in normal-appearing flat colonic mucosa (field defects) may predispose individuals to colon cancer. Markers of field defects would indicate cancer risk.
METHODS
We evaluated apoptosis capability, dedifferentiation, frequency of simple aberrant crypts, aberrant crypt foci,
Recognition of a high molecular weight glycoprotein (HMW-GP) associated with rat colon cancer cells by rat monoclonal antibodies.
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Σύνδεση εγγραφή
In this report we describe an auto-immunogenic tumor associated high molecular weight glycoprotein (HMW-GP) present on most rat colon carcinomas as detected by syngeneic monoclonal IgM antibodies. The HMW-GP has an apparent molecular weight of more than 10(6) D and carries several epitopes for
Lectin histochemistry of galactose and N-acetyl-galactosamine glycoconjugates in normal gastric mucosa and gastric cancer and the relationship with ABO and secretor status.
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Σύνδεση εγγραφή
The histochemical binding of four lectin-peroxidase conjugates to normal human gastric mucosa and gastric carcinoma is described. The lectins were peanut agglutinin (PNA) which is specific for galactose residues and soy bean agglutinin (SBA), Dolichos biflorus agglutinin (DBA) and Helix pomatia
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