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linum/αντικαρκινικός
Ο σύνδεσμος αποθηκεύεται στο πρόχειρο
Σελίδα 1 από 29 Αποτελέσματα
Effect of aeration on production of anticancer lignans by cell suspension cultures of Linum album.
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Σύνδεση εγγραφή
The effects of aeration within the range of 0.2-0.5 vvm on transformed and high yielding cell cultures of Linum album were investigated in a 5-L stirred tank bioreactor equipped with low shear Setric impeller. The kinetics of cell growth, substrate utilization, and production of lignans, namely,
Potential anticancer agents II: antitumor and cytotoxic lignans from Linum album (Linaceae).
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Σύνδεση εγγραφή
A phytochemical study of Linum album (Linaceae), guided by bioassay with the 9KB cell culture, resulted in the isolation of podophyllotoxin and a new lignan, 3'-demethylpodophyllotoxin; alpha-and beta-peltatins were identified by comparative TLC.
Selection methodology with scoring system: application to Mexican plants producing podophyllotoxin related lignans.
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As most anticancer drugs are derived from natural sources, the screening of local medicinal flora should be considered a primary step in the search for new sources for antineoplastic agents. In Mexico, more than 6000 medicinal plant species are used for the treatment of various diseases, including
In vitro polyploidy induction: changes in morphology, podophyllotoxin biosynthesis, and expression of the related genes in Linum album (Linaceae).
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UNASSIGNED
Induction of tetraploidy was performed and podophyllotoxin production increased by upregulating the expression level and enzyme activity of genes related to its biosynthesis in tetraploid compared to diploid Linum album. Linum album is a valuable medicinal plant that produces antiviral
A review on Pharmacological and clinical aspects of Linum usitatissimum L.
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BACKGROUND
Linum usitatissimum L., known as common Flax or linseed, from the family Linnaceae, has long been cultivated in different nations due to its applications in medicine and industry. The present study aims to collect nearly all available information about chemical constituents of Flax, as
The Apoptotic, Cytotoxic, and Antiangiogenic Impact of Linum usitatissimum Seed Essential Oil Nanoemulsions on the Human Ovarian Cancer Cell Line A2780
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Background: Linum usitatissimum seed essential oil (LSEO) has been used to reduce the risk of prostate and colon cancer. In this study, we optimized the bio-accessibility and bio-compatibility of LSEO to evaluate its cytotoxic,
Orbitides isolated from flaxseed induce apoptosis against SGC-7901 adenocarcinoma cells.
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Unique plant-derived cyclic peptides family exhibiting various key biological activities has great possibility for anticancer therapy. In this study, we investigated the effects of orbitides isolated from flax (Linum usitatissimum L.) on the growth of SGC-7901 cancer cells and the potential
[Phytoestrogenis properties of flaxseed lignans].
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The analysis of experimental, clinical and epidemiological data on the phytoestrogen properties of the components of flaxseed Linum Usitatissimum L., especially lignans and products of their biotransformation in humans and animals enterodiol (END) and enterolactone (ENL) are presented. Flaxseed is
Kinetic Interactions between Cyclolinopeptides and Immobilized Human Serum Albumin by Surface Plasmon Resonance.
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Cyclolinopeptides (CLs) are octa-, nona-, and decapeptides present in flaxseed (Linum usitatissimum L.) that may have immunosuppressive and antitumor activities, but little is known of their pharmacokinetics. Human serum albumin (HSA), the most abundant blood protein, is an important mediator of
De Novo Transcriptomes of Forsythia koreana Using a Novel Assembly Method: Insight into Tissue- and Species-Specific Expression of Lignan Biosynthesis-Related Gene.
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Forsythia spp. are perennial woody plants which are one of the most extensively used medicinal sources of Chinese medicines and functional diets owing to their lignan contents. Lignans have received widespread attention as leading compounds in the development of antitumor drugs and healthy diets for
Optimization of podophyllotoxin extraction method from Linum album cell cultures.
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BACKGROUND
Suspension cultures of Linum album Kotschy ex Boiss. (Linaceae) accumulate podophyllotoxin (an anticancer agent) and could therefore serve as an alternative source of this important aryltetralin lactone lignan.
OBJECTIVE
The present work compared four podophyllotoxin extraction methods
Time-course changes in fungal elicitor-induced lignan synthesis and expression of the relevant genes in cell cultures of Linum album.
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Linum album has been shown to accumulate anti-tumor podophyllotoxin (PTOX) and its related lignans. In the present study, we examined the effects of five fungal extracts on the production of lignans in L. album cell cultures. Fusarium graminearum extract induced the highest increase of PTOX
Kinetics of glucosylated and non-glucosylated aryltetralin lignans in Linum hairy root cultures.
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Σύνδεση εγγραφή
Due to their pronounced cytotoxic activity, a number of aryltetralin lignans (ATLs), such as podophyllotoxin (PTOX), are used as antitumor compounds. The production of such molecules from entire plants or plant cell-tissue-organ cultures is thus of interest to the pharmaceutical industry. Hairy root
Induction of apoptosis in leukemia cell lines by Linum persicum and Euphorbia cheiradenia.
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OBJECTIVE
In the present study two medicinal herbs Linum persicum and Euphorbia cheiradenia that are native to Iran were tested for their possible anticancer effect and induction of apoptosis on human tumor cell lines including leukemia cell lines.
METHODS
The effect of methanolic extracts of the
Cytotoxic activity of a podophyllotoxin-like lignan from Linum tauricum Willd.
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The present study describes the preliminary evaluation of the cytotoxic activity of a podophyllotoxin-like compound 4'-demethyl-6-methoxypodophyllotoxin (4'-DM-6-Mptox), isolated as one of the main lignans of Linum tauricum Willd. ssp. tauricum. The cytotoxic effects 4'-DM-6-Mptox were assessed by
Η πληρέστερη βάση δεδομένων φαρμακευτικών βοτάνων που υποστηρίζεται από την επιστήμη
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Πληκτρολογήστε ένα σύμπτωμα ή μια ασθένεια και διαβάστε για βότανα που μπορεί να βοηθήσουν, πληκτρολογήστε ένα βότανο και δείτε ασθένειες και συμπτώματα κατά των οποίων χρησιμοποιείται.
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